24 results
To study the effect of the interaction of cyclooxygenase-2 (COX-2) inhibition (started preoperatively and continued 5 days into the postoperative period) and extended local anaesthetic blockade via paravertebral block on postoperative central…
In line with results from recent pharmacological studies, it is expected that: 1. Inhibiting the cholinergic system by Inversine (Mecamylamine Hydrochloride) results in an impairment of disengagement, but will not affect bias; 2. Inhibiting the…
The primary objective is to demonstrate the non-inferiority of bevacizumab to ranibizumab in the treatment of patients with subfoveal CNV secondary to AMD as determined by the change in best-corrected visual acuity in the study eye from baseline to…
This study was therefore designed to determine whether cinnamon lower postprandial blood glucose, and insulin levels in subjects with type 2 diabetes or impaired glucose tolerance.
The investigational anti-reflux formula will be equivalent to the currently marketed control anti-reflux formula with regard to intestinal tolerance during eight weeks in infants with regurgitation.
Dietary management of nutrient deficiencies with the medical food under study has a positive effect on cognitive performance in patients with prodromal Alzheimer's Disease.
A home-based peripheral muscle training program (Five Basic Exercises program (5BX)) is more effective in [a] increasing exercise capacity (e.g. peak work rate) and [b] patients’ preferred occupational performance when it is preconditioned by…
This study is therefore aimed at quantifying the relative contribution of the two major receptor systhems involved in S(+) ketamine and methadone induced analgesia and side effects( respiratory depression,sedation,miosis).
Progesterone treatment for women with a short cervical length is effective in reducing the risk of preterm delivery.
It is expected that modafinil improves cognitive functioning in abstinent alcohol dependent patients, increases time to first relapse and reduces relapse rates and relapse severity. In addition, it is expected that participants with different…
The investigational formulae are equivalent to the currently marketed control formula with regard to weight gain of healthy full-term infants during first 16 weeks of life.
Is docetaxel weekly as effective and less toxic than the same dose given 3-weekly.
A relatively high quantity of dietary protein is needed to stimulate muscle protein synthesis in elderly.
De hypothese is dat bekkenfysiotherapie de obstipatieklachten bij kinderen gunstig kan beinvloeden.
The endocannabinoid system is involved in cognitive functioning, and therefore, challenging this system with THC will influence cognitive processing in humans. Moreover, subjects with cognitive impairments (i.e. psychiatric patients) will react…
We hypothesize that PEMF-treatment will be of additional value after the primary arthroscopic treatment of an OD, and the resumption of sports can be both improved and accelerated.
Genestein inhibits the synthesis of heparan sulphate and can possibly slow down disease progression in Sanfilippo Syndrome patients.
Activation of SIRT1 (silent information regulator transcript) results in inhibition of inflammation in humans.
Recent clinical data showed that remote ischemic preconditioning attenuates myocardial damage during cardiac surgery. Classic preconditioning is abolished in diabetic patients. We will investigate the molecular effects of remote ischemic…
To compare the differences in duration of delirium in delirious patients receiving anti-psychotic therapy + melatonin or anti-psychotic therapy + placebo.