96 results
Obesity is a growing world wide problem. In The Netherlands, about 10% of all men and women have a BMI of 30 kg/m2 or more. Obesity is a chronic, uncurable metabolic disorder, which is characterised by excessive fatstorage at unfavorable places.…
To evaluate the cost-effectiveness of therapies for male subfertility.
1. Active sniffing decreases appetite; 2. Food choice is mainly influenced by the food odour that was perceived first.
The hypothesis is that testosterone supplementation improves functional mobility, quality of life, body composition, cognitive function, aortic stiffness and cardiovascular risk factors, and bone mineral density compared to placebo.
A low peak E2 during COS is considered to be safer than a high peak E2 in women with breast cancer
Since bleeding risk is high in the elderly we hypothesize that clopidogrel is superior to ticagrelor and prasugrel in terms of causing lesser bleeding events and being non inferior in net clinical benefit in patients above 75 years and CRUSADE…
The aim is to evaluate molecular assays for the detection and quantification of bacterial DNA in blood from patients with bacteraemia.
Information on the dynamics and shape of the device and how these change over time will improve our understanding about the fixation and/or sealing of the device, which may help in stent selection and in designing stent grafts that are more durable.
Aim of this prospective randomized trial (RCT) is to compare the gold standard LCW with the CWO in patients eligible for HTO who need a correction of 10 to 16 degrees. Hypothesis is that the CWO technique will achieve more accurate overcorrection of…
An online intervention will be an effective intervention for treating affective symptoms in pregnancy and their complications by reaching more women and making therapy easier accessible
Primary: are there differences between the online course group and the control group in the change in depressive complaints from baseline to follow-up measurements? Secundary: Is the intervention cost-effective compared to a no preventive…
Objectives Primary: To examine the effects of regular glucose lowering treatment on inflammatory markers in type 2 Diabetes Mellitus Secondary: To identify markers/fingerprints that predict the response of a patient to glucose lowering therapy in…
We aim to test the hypotheses that offering additional online adaptive coaching to a web-based self-management program will be more effective than a web-based self-management program without coaching in terms of self-management behaviour without…
Endocuff colonoscopy will increase the number of adenomas detected.
we would like to investigate whether multiple fecal transplantations using either allogenic (lean preferably vegetarian/vegan donor) or autologous (own) donors have a beneficial effect on non alcoholic steatohepatitis (NASH) using biopsy and MRI…
In this observation study we hypothise an incidence of UTIs of 30% in the first year after starting CIC. Moreover we hypothise a marked reduction in quality of life and an increase in health care expensis in patients with UTI.
Authors hypothesized that the physical extracorporeal shock wave (ESW) stimulation will decrease the resting muscle activity of paralysed forearm muscles, reducing the degree of spasticity in surface electromyography examination as well as Modified…
A lower amount of cold soluble galactomannans (0.33g per 100ml) is as effective as 0.45g/100ml of hot soluble galactomannans in reducing the number of visible and invisible refluxes.
The maternal diet is highly responsible for the composition of breast milk which will result in at least differences between cultures and geographical separated populations. The maternal diet and breastmilk composition will show off in the…
Microspirometry result in a higher proportion of diagnostic spirometric assessment to objectify the existence or absence of a chronic airflow obstruction within 3 months after a patients at risk for COPD visited the GP compared to usual care.