179 results
To test the effectiveness of a self help booklet without therapist guidance vis-à-vis a psycho-education brochure for adult problem drinkers in the general population.
To study the effect of the interaction of cyclooxygenase-2 (COX-2) inhibition (started preoperatively and continued 5 days into the postoperative period) and extended local anaesthetic blockade via paravertebral block on postoperative central…
The induction of immunity might be slower in older persons than in younger individuals. This could influence the occurence of adverse events induced by the vaccine.
Non-inferiority (defined as < 12.5% increase) of pooled buffy coat-derived PR platelet concentrates (PR-plasma-PCs) compared to plasma (plasma-PCs) in terms of clinical efficacy determined by WHO grade ≥ 2 bleeding complications.
In line with results from recent pharmacological studies, it is expected that: 1. Inhibiting the cholinergic system by Inversine (Mecamylamine Hydrochloride) results in an impairment of disengagement, but will not affect bias; 2. Inhibiting the…
The primary objective is to demonstrate the non-inferiority of bevacizumab to ranibizumab in the treatment of patients with subfoveal CNV secondary to AMD as determined by the change in best-corrected visual acuity in the study eye from baseline to…
Suppression of SWS, without changing total sleep time, may affect total energy expenditure (TEE), activity induced energy expenditure (AEE), non-exercise activity thermogenesis (NEAT), endocrinological parameters and energy intake.
To assess the effect of statin therapy on the process of atherosclerosis in type 2 diabetes without manifest cardiovascular disease.
1. In Barrett Esophagus (BE), probe-based laser endomicroscopy (pCLE) provides better correlation with the histological diagnosis compared to detailed inspection with Narrow Band Imaging (NBI), reducing the high rate of false-positive findings with…
This study was therefore designed to determine whether cinnamon lower postprandial blood glucose, and insulin levels in subjects with type 2 diabetes or impaired glucose tolerance.
The general objective of the DECREASE-IV trial is to assess the clinical efficacy of beta-blocker therapy, statin therapy and combination therapy with beta-blockers and statins in patients undergoing major noncardiac surgery.
Detection of chronic pain in adolescents by self-report combined with advice from a school nurse will be efficient and effective.
It is expected that the new pre-thickened sip feed is as safe as and well-tolerated as standard sip feed thickened with a commercially available thickener.
The investigational anti-reflux formula will be equivalent to the currently marketed control anti-reflux formula with regard to intestinal tolerance during eight weeks in infants with regurgitation.
The healing of donor site wounds after split-skin grafting can be promoted by the use of one of five specific wound dressing materials as compared in this trial.
1. The effect of cognitive behavioral therapy in internettherapy and face-to-face therapy is larger then without therapy on women with a sexual dysfuntion; 2. The impact of Internet therapy is just as large as the impact of treatment-as-usual (face-…
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Improving the immunological status of HIV-1 infected adults not on antiretroviral therapy through nutritional support.
Hypothesis: the working mechanims of metformin can be partly explained by its effect on the composition of the gut microbiota, with changes in inretin secretion and inflammatory pathways as secondary effects.
Dietary management of nutrient deficiencies with the medical food under study has a positive effect on cognitive performance in patients with prodromal Alzheimer's Disease.