197 results
We hypothesize that group medical appointments will enhance adherence to treatment and self-efficacy in patients with sickle cell disease, as well as increase quality of life, and satisfaction with the treating physician and nurse. When performing…
The primary research questions are: 1. To what extent does a 4 week ReHab-TOAT regime lead to improvement of arm function in chronic stroke patients with either a severely or moderately affected arm-hand? 2. To what extent is any improvement of arm…
Based on previous studies, we will expect that ambroxol improves neurological manifestations in patients with GD3.
We hypothesize that PARP inhibitors can potentiate radiation-induced tumor cell death in patients treated with PRRT. To determine the maximin tolerated dose (MTD) of this combination, a phase 1 dose-escalation study is needed.
Short hydration during cisplatin chemo radiation is significantly more effective than long hydration in preventing acute kidney injury
The aim of the pilot trial is to: 1. evaluate the potential effectiveness and effect size of the e-support program for parents of children with a chronic kidney disease; 2. to identify outcome measures most likely to capture potential patient…
The aim of this study is to evaluate the effects of platelet transfusions on hemostatic parameters in thrombocytopenic hematology patients and to identify other determinants of hemostasis, which may contribute to clot formation and clot strength.
We hypothesize that there will be a significant difference in anterior translation of the humeral head between patients and healthy objects. Secondly we hypothesize that the inter- and intra-rater reliability of the HHC test will be fair to good.…
Pulmonary rehabilitation prior to bariatric surgery is effective by means of outcome (asthma control, complications, recovery, physical condition, quality of life) after the bariatric surgery.
We expect that when the developed checklist will be used in de diagnostic proces of children with developmental and/or behavioral disability, the use of pediatric care will be more efficiently used. Over and underdiagnoses of a causal somatic…
Effectivity of information transfer between ambulance personnel and hospital staff (% content using SBAR system) Efficiency of information transfer between ambulance personnel and hospital staff (time)
The main hypothesis is that normo-ovulatory women with a deleterious BRCA mutation have lower levels of AMH compared to normal controls, with at least a difference of 0.90 ng/ml, suggesting an effect size of approximately five years in menopausal…
A subset of patients with ulcerative colitis have disease limited to only the rectum. Most patients will reach remission with conventional 5-ASA or corticosteroid treatments. However, there have been few studies investigating treatment options in…
The primary objective is to investigate the effectiveness of a personalized 2-year multidomain lifestyle intervention on cognitive performance in older adults at risk of cognitive decline.
It is hypothesized that the orientation of the lower limb joints are not parallel to the walking direction and that a standing measure is highly correlated with the orientation during the standing, load bearing, phase of the gait cycle.
The hypothesize is, that treatment with induction chemotherapy will lead to a 15% increase of the R0 resection rate compared to treatment with neoadjuvant chemoradiotherapy and surgery alone.
There is no difference between patients managed with a decision aid compared to patients not managed with a decision aid, regarding the decision of conflict scale.
The main aim of this project is to conduct a pilot randomized controlled trail (RCT) to evaluate the preliminary effectiveness and feasibility of cognitive behavioral therapy (CBT) as an intervention for relatives of long-term missing persons. The…