21 results
Determine whether feedback by means of motivational gaming can (partially) restore cognition-related deviations in motor performance as seen in back challenging conditions in CLBP patients.
Is subjective fatigue in patients with MS related to a combination of force reduction during a fatiguing task and depression score?
To investigate if there are differences in serotonin transporters in the hypothalamus between subjects with hypopituitarism suspect for hypothalamic damage, subjects with hypopituitarism and no suspicion of hypothalamic damage and healthy age- and…
The aim of this project is to determine optimal communication strategies for prognostic disclosure in the palliative phase of breast cancer from a patient perspective. Study 1: To explore breast cancer survivors*, healthy women*s and oncologists*…
First, to measure the influence of the speech coding strategy on frequency discrimination in a free field test. Second, to quantify the influence of the number of harmonics on frequency discrimination in cochlear implant users and in normally…
Can clinical experience be related to activation differences using fMRI? On the basis of previous studies by Schmidt cs. (Erasmus University Rotterdam and one of the investigators in the present study) it has been demonstrated that clinical…
The objective of this study is to learn from young people with a chronic illness (diabetes or progressive muscular disease) who have found a balance between taking good care of their illness and having a good life. This study examines how these…
Primary objective:* To analyze the association between single nucleotide polymorphisms (SNP) markers and treatment response. Treatment response is based on the Expanded Disability Status Scale (EDSS) progression and relapse outcomes over the first 2…
Investigate how S1 and the premotor cortex modulate the cortico-spinal excitability as measures by single pulse TMS stimulation of M1.
The primary objective of this study is to understand how individual differences in structural anatomy, structural connectivity, and functional connectivity are related to individual differences in cognitive function among healthy older adults. A…
Test efficacy of compound B in humanized mouse model of psoriasis.
The primary objective of this sutdy is to further investigate attention and MSI in adolescents with ASD. To do so, the following tasks will be administered. Task 1 Clock task: multisensory integration and the effect of sound on the velocity of the…
There are multiple objectives to this study. First, we want to find a way of controlling the prosthesis using electromyography (EMG) of the muscles left in the stump. Secondly, we want to find a way to give feedback to the human during certain *…
To investigate the validity the dynamometer the KinCom in comparison to the Biodex dynamometer.
Primary objective: to determine the effect of intake of one dose of isoflavones, as compared to placebo, for eight weeks on gene-expression in Peripheral Blood Mononuclear Cells (PBMCs) in post-menopausal, equol-producing women.Secondary Objectives…
Feasibility of laboratory monitoring in community pharmacies by Point-Of-Care testing creatinine and potassium in ambulatory elderly at risk for impaired renal function.
The principle aim of this study is to characterise all of the genetic alterations that are present in different types of breastcancer by comparing the cancer genome to it's matched normal genome.The primary goals of this ICGC project, which…
To investigate the effects of three different methods of finding a suitable recording site for CMAP and three different electrode sizes on CMAP amplitude and its reproducibility
To establish the presence of direct trans-intestinal cholesterol excretion (TICE) in humans by faecal recovery of i.v. administered 13C-cholesterol in patients with a total biliary obstruction. This is a so-called proof-of-concept study.
The objective of the studie is to develop a reliable and discriminative measurment protocol to determine the upper extremity function in boys with DMD. This measurement protocol will be based on 3D movement analysis and surface EMG measurements.