147 results
This multicentre randomised controlled trial aims to investigate whether PoCUS can be used as an adjunct to improve first attempt success rate in closed reductions of displaced distal radial fractures in adults in the ED.
The primary objective of this study is to measure the effectiveness of the TFT for URMs living in the Netherlands. The research question is as follows: is this TFT effective in decreasing symptoms of posttraumatic stress and depression in URMs…
1. Explore the diagnostic value by comparing muscle volume, fatty infiltration and oedema/inflammation using qMRI in MG patients, healthy controls and MG mimics (other neuromuscular diseases and Graves* ophthalmopathy (GO) patients).2. Explore the…
Primary objective:Is guided online treatment, based on CGT with mindfull- and exposure exercises, with minimal patient contact, effective for IBS-patients as compared to a waiting list?Secondary objectives: Will the guided online treatment lead to…
The study aims to quantify differences in gastric digestion and absorption of caprine and bovine casein protein
To study the effect of sweetener oral rinses on the oral microbiome composition.
Primary Objective: The primary objective is to establish the differential and sequential effectiveness of cognitive restructuring (CR) and behavioral activation (BA) (and the optimal sequence of these elements) on depressive symptoms (PHQ-2 at post…
Assessing the post traumatic and degenerative radio-carpal osteoarthritis of open reduction and internal fixation compared with non-operative treatment for elderly patients with an intra-articular distal radius fracture.
The primary objective of this study is to assess the effect of audio-visual immersion on pain perception in patients undergoing a short surgical procedure (a.i. wrist fracture reduction) under local anesthesia in the Emergency Department (ED).…
To evaluate whether supplementation of vitamin K2 decelerates the rate of mature cross-linked elastin degradation inpatients with COPD.
BEWARE 2.0: body awareness training for wearing-off related distress in Parkinson's disease patients
Do patients that receive the BEWARE training have a higher score on the Chronic Illness Acceptance Questionnaire at the end of treatment (and at 3 month follow-up) compared to the treatment as usual (physical therapy only)?
To explore cardiovascular remodelling with subsequent altered cardiac function (assessed as strain rate) in extremely premature neonates (born <30 weeks and/or birth weight < 1000 gram) with FGR.
Primary Hypothesis: - There is a difference in PROMIS Physical Function Upper Extremity Short Form (PROMIS PF UE SF) score between group A (6 weeks distraction) and group B (8 weeks distraction) at 1 year after first carpometacarpal joint…
The aim of this study is to investigate the use of spirometry, forced oscillation technique (FOT), and negative expiratory pressure (NEP) in both protrusion and retraction of the mandible as prediction measurements for MAD success.
To investigate whether microbial transplantation from either allogenic (healthy) or autologous (own) donor, administered every 8 weeks during 6 months through a small intestinal tube, has beneficial effects on residual thyroid function at baseline,…
Primary Objective: Determine the value of trans-impedance measurement (TIM) for detection of new bone formation (NBF).Secondary Objective(s): Determine the influence of NBF on electrophysiological parameters, residual hearing and speech perception…
Primary objective: To obtain insight into signature of immune responses triggered by a bivalent- or nonavalent HPV vaccination (three-dose schedule). Secondary objectives: To determine the most informative time-points to study different innate and…
To assess the efficacy of LEX0 on the calf for Restless Legs (RLS)
The study objective is to test the effect of a tDCS intervention in a sample of healthy military personnel. We investigate the effects of the intervention primarily on the intensity of fear reactions, and secondarily on cognitive performance and…
The primary objective is to investigate if models are able to predict changes in blood glucose levels in patients with T2DM when small changes in dietary intake and/or physical activity are applied.