26 results
In this randomised controlled trial we compare three commonly used preventive methods to reduce the pain on injection op (PIP) with a control group. Our primary goal is to try and establish the most effective and easy to use method for preventing…
The possibility to identify the risk of rupture of a carotid plaque will have tremendous impact in clinical decision making. Selection of candidates from surgery is based mainly on duplex ultrasonography, where now only the size of the stenosis is…
The objective of the study is to improve the peri-operative care for fragile older patients who have been indicated for elective surgery of thorax and abdomen.
1. to compare the extent of reversal of left ventricular remodelling at 3 months and 1 year after a TAVI procedure between patients with a TAVI-induced LBBB and patients without a LBBB; 2. comparison of strain patterns in TAVI-induced LBBB (as being…
To investigate whether application of APLG will lead to reduction in: 1) sternal wound infections 2) vessel harvest site infections 3) postoperative blood loss 4) postoperative pain
Objective is to study the implementation of a proven cocept for active primary prevention of type 2 diabetes in a Dutch primary care setting, in order to assess whether such a concept can be applied on a broader scale, and as such contribute to the…
To evaluate the accuracy of trained hypo-alert dogs and to evaluate the quality of life of patients with such a dog.
The primary objective of this study is to investigate whether application of PRF® will reduce postoperative wound leakage, the necessity for allogeneic blood transfusions and the incidence of wound healing disturbances in patients undergoing…
To study the interaction between normal T lymphocytes and Hodgkin tumor cells in an in vitro model.
To investigate whether treating children with high refractive errors at age one with glasses prevents the development of amblyopia.
The primary objective of this study is to investigate whether the use of the EOS calculator safely reduces antibiotic exposure in newborns with suspected EOS in the first 24 hours after birth compared to the current Dutch guidelines.Secondary…
The primary objectives of the pilot study are: 1. To determine a successful strategy for recruiting and following-up participants during their transition phase from home to a nursing home; 2. To determine the suitability of the study procedure; 3.…
Objectives: - To identify and compare motivational behaviour in patients during different phases of cancer treatment. - To test its associations with self-reported fatigue/depression. - To determine to what extent treatment regimen, inflammation,…
The aim is to provide enough evidence through RifRam model analysis, physical tests and clinical study of 10 patients that our new type of personalized mandibular implant is safe to use, resulting in significantly fewer complications and can be…
Primary objective:Does the use of the application support a positive lifestyle development?Secondary objectives:Does the use of the application support an increase in physical activity levels?Does the use of the application has a positive influence…
In this study the primary objective is to investigate whether activation of TRPV1, TRPA1 and TRPM3 by selective channel agonists induces vasodilation in human dermal arteries. If the primary objective is achieved, the secondary objective is to…
For this reason, we will conduct an intervention study aimed at promoting the health of (future) parents. The concrete goal of this intervention is to improve the health of (future) parents by optimizing lifestyle in the preconception period and…
Primary objectives: To evaluate the efficacy of long-term prophylactic treatment with deucrictibant (PHA-022121) in preventing breakthrough angioedema attacks in patients with AAE-C1-INH. Secondary objectives: To evaluate the safety of long-term…
Objective: to evaluate the effects of MOF in comparison to placebo on exercise blood pressure, endothelial function, inflammatory and redox status in healthy volunteers. In addition, the study will aim to assess the impact of MOF supplementation on…
The first objective of this study is to provide a detailed, quantitative and qualitative description of early language development (*developmental language profile*) in children with 22q11DS, comprising expressive and receptive abilities, covering…