40 results
does the use of fluticasone as an inhaled corticosteroid influence the determination of saliva cortisol?
To predict the risk of particular coronary plaques to cause myocardial infarction
The identification of axial SpA in the primary-care setting and the introduction of questionnaires that could optimize the pattern of referral to secondary care is one of the most important objectives of the CAFASPA-II study.
Primary Objective: To determine T cell response to Coxiella burnetii antigens using an ELISPOT interferon gamma release assay in patients with different clinical outcomes after acute Q fever
To propose a regional staging protocol, lymphatic mapping and sentinel node biopsy, for patients with locally recurrent breast cancer in the absence of guidelines for regional staging procedures and to registrate data derived from this study.
Evaluation of I-FABP as diagnostic tool in mesenteric ischemia.
To compare oesophageal motility as well as refluxcharacteristics before and after endoscopic treatment of the Barrett segment, and to study differences between patients treated with SRER or BÂRRx.
To assess the influence of bloodpressure, wall thickness, wall properties, and geometry changes throughout the cardiac cycle on the wall stress calculations. Previous analysis were performed with an assumed bloodpressure value, an uniform wall…
the proposed study will examine the differences in flow-mediated vasodilatation of the brachial artery in depressed and non-depressed post-MI patients.
To investigate the clinical value of OptiVol (TM) impedance measurement by Medtronic(R) InSync Sentry(TM) ICD's. We aim to determine specificity and sensitivity for detecting heart failure. With collected data we want to design a protocol for…
To establish the value of a new, sensitive tropnion I assay in the rapid diagnosis of minimal myocardial damage.To establish whether BNP concentration in the blood of patients with acute, minor myocardial damage has prognostic significance.
The main objectives are :Cross-sectional:1. To investigate the extent of atherosclerotic disease of the carotid artery defined as: (a) the intima-media thickness (IMT) (b) the elasticity (c) the degree of stenosis2. To define the degree of…
Validation of stent boosting technique for optimum stent deployment compared to intravascular ultrasound (IVUS).
If the hypotheses of this study are confirmed, this might have important implications for the allocation of patients to group or individual treatments. As it is expected that patients with limited mental flexibility and empathy experience less group…
1) To investigate what mechanisms underlie the phenomenon of deventilation dyspnoea in COPD patients. 2) To investigate how the change in electrical impedance, measured with electrical impedance tomography (EIT), is related to the change in…
Primary Objective: The primary outcome of this study is successful implementation of home-based blood sampling. The success criteria is that 25% or more of the blood assessments are actually performed at home by the patients themselves using a self-…
Possible correlations between blood and sweat composition will be investigated. If these correlations exist, sweat composition can be related to phenomena like dehydration. In this way, invasive measurements may become unnecessary in elite sport and…
The primary objective of the CATCA-study is to develop a cfDNA based screening/surveillance tool for colorectal adenoma and cancer, both in the setting of the national CRC screening program and in the surveillance of LS carriers. Additionally, we…
The Biobank 'Leukemia, Myeloma, Lymphoma and Myelofibrosis' has the scientific objective of gaining insight in molecular-biological and environmental factors, that are involved in the development of malignant hematological diseases such as…
• Characterization of methylation patterns in blood samples and finding of methylation patterns that are unique to lung cancer.• Development of a molecular test for early diagnosis of lung cancer from a blood sample that will be more sensitive and…