17 results
1. To determine biomarkers of response and non-response to treatment for active SLE in a prospective study where patients will be allocated to therapy according to current clinical practice and the EULAR guidelines (response biomarker study; 3TR SLE…
The current project has two goals: (1) to measure viewing strategies used by children with normal vision, children with ocular visual impairment and children with CVI and (2) to evaluate whether training viewing strategies results in more efficient…
The primary objective of the clinical performance study is to demonstrate the clinical performance of VENTANA PD-L1 (SP263) CDx Assay in terms of its ability to identify NSCLC patients who may benefit from treatment with volrustomig plus…
The overall objective is to perform simulations in a computer model of the human brain to map out the optimal parameters for non-invasive brain stimulation in AD. Simulations will be performed in both general and personalised models, the latter…
The aim of this trial is to determine if CR in patients with a displaced DRF can be safely abandoned before the plaster cast, as a bridge to surgery, is applied. This could prevent a painful and traumatizing experience and therefore benefit the…
Primary objective is to investigate the effect of VR on patient-reported pain outcomes in the ED. Secondary objectives are to investigate the effect of VR on analgesics use, patient-reported outcomes, and process indicators and to identify barriers…
1. To evaluate the feasibility of 68Ga-FAPi PET/CT in detecting intestinal fibrosis in patients with IBD2.To optimize the acquisition and reconstruction methodology and identifying simplistic uptake measurements for FAPi PET/CT for detecting and…
Primary: - Examine longitudinal developmental trajectories of structural and functional brain metrics in relation to genetic, clinical, psychological, environmental, and cognitive information in familial high-risk offspring and control children (…
The primary objective of this study is to assess whether laser hair removal therapy improves the course and severity of mild to moderate HS, as assessed by the difference in IHS4 between groups over time between month 7 to month 12.
The LIMONCELLO study aims to assess the effect and cost-effectiveness of TMPC compared to usual care.
Phase 1 Part (Dose-escalation and Expansion):Primary objective:To evaluate the safety and tolerability of TK-8001Secondary objectives:To evaluate the preliminary anti-tumor activity of TK-8001 To determine the recommended Phase 2 dose (RP2D) of TK-…
To determine the effect of a 6-month eucaloric very-low-carbohydrate ketogenic diet on IGF-I levels in adult acromegaly patients.
This study aims to assess the safety and efficacy of the remed*® system in adult patients with moderate to severe central sleep apnea in real life.
Primary objective:Investigating the effect of the use of cryo- and compression therapy during the first 6 postoperative weeks after surgery (TKA en UKA) on the perceived pain in rest at 6 weeks postoperative.Secundary objectives:Investigating the…
Our objective is to assess the association between transcutaneous diaphragm electromyography (dEMG) and diaphragm ultrasound (dUS) in the PICU population.
The aim of this study is to identify whether the availability of a PSD for military veterans with PTSD coincides with clinically significant changes in wellbeing, behaviour and functioning in veterans and their families compared to veterans with…
Primary objectives: To evaluate the efficacy of long-term prophylactic treatment with deucrictibant (PHA-022121) in preventing breakthrough angioedema attacks in patients with AAE-C1-INH. Secondary objectives: To evaluate the safety of long-term…