62 results
our primary aim is to validate a targeted analysis of circulating DNA in maternal blood by assessing the diagnostic accuracy for fetal trisomy 21. In addition, test characteristics for fetal trisomy 18 detection will be evaluated.
In this study we want to prospectively investigate in a large ambulatory surgical cohort in which patients glucose levels increase during surgery and whether this is related to postoperative complications.
1. Examen if the outcome of the 1 mg Overnight Dexamethasone suppression test is influenced by the use of oral contraception.2. Examen how many weeks after ceasing the use of orale contraception the 1 mg Overnight Dexamethason suppression test is…
Aim of the project is to determine whether it is possible to implement a CAT for the identification of children with psychosocial problems in Dutch JGZ. Additionally the study will evaluate the CAT as it is being used in practice. The trial…
To document cardiac function before and after treatment of CS.
What is the diagnostic accuracy of the schoolAMPS for children with DCD in the age of 6 to 11 year, compared to typical developing children in the same age, in the Netherlands? With diagnostic accuracy is meant: is it possible with the schoolAMPS to…
In the current study we will measure CVI in ASA 1-3 patients during elective abdominal surgery under fentanyl/sevoflurane/epidural anesthesia. We will monitor patient movement as primary correlate to CVA and cardiovascular parameters as secondary…
Determine wether or not a strategy based on molecular analysis is effective in improving the PFS
The aim of this study is to compare the sensitivity of chromoendoscopy with Lugol*s solution with conventional white light video endoscopy in diagnosing esophageal dysplasia and cancer in patients with achalasia.
This project aims at evaluating the reliability, validity, and the added value of the SDQ (Parent Format ) compared to LSPPK (a Dutch questionnaire to detect psychosocial problems in toddlers and children). The study findings may support the Dutch…
Objective: Evaluation of the supposed correlation between increased serum and urine NGAL levels (> 350 ng/ml) and significant increases in serum creatinine levels in adult ICU patients compared to preclinical levels
The general aim of this study is to explore how a motivational deficiency (i.e. apathy) related to neurodegenerative diseases is associated with effort and how it can be distinguished from intentional underperformance. We will investigate whether…
The objective for this trial is to evaluate an invasive strategy using urgent PCI (<3h) as compared to an early PCI (24h) using novel quick acting antiplatelet therapy.
The primary objective of this study is to investigate whether SCS combined with best (drug) treatment as usual (TAU) leads to clinically significant (>=50%) pain relief in patients suffering from moderate-to-severe PDP in the lower limbs…
To examine the 1- and 3-year prognostic value of the CAR-test in patients with peripheral artery disease regarding the occurrence of vascular complications and the progression of PAD
To investigate whether the amount of TiMas containing brain specific proteins, correlates with functional outcome and infarct size in patients with acute ischemic stroke. And, to study the kinetics of the tissue macrophages and to compare these data…
(i) to determine specificity of Q-detect* for registration purposes. (ii) to design a decision tree for follow-up of patients with a positive Q-detect* and
To establish benchmark values in healthy control fetuses, to compare these with our cohort of fetuses with severe CHD.
To compare the performance and diagnostic accuracy of two EUS-guided tissue acquisition devices; a 25G Echotip Ultra Fine Needle Aspiration (FNA) device and a new, more flexible, 20G Echotip ProCore Fine Needle Biopsy (FNB) device.
To gain insight into the measurement properties of three questionnaires (part I) and the measurement properties of the upper limb functional capacity evaluation (part II). To gain insight in the effects of disorders of hand or wrist on health-…