62 results
our primary aim is to validate a targeted analysis of circulating DNA in maternal blood by assessing the diagnostic accuracy for fetal trisomy 21. In addition, test characteristics for fetal trisomy 18 detection will be evaluated.
In this study we want to prospectively investigate in a large ambulatory surgical cohort in which patients glucose levels increase during surgery and whether this is related to postoperative complications.
1. Examen if the outcome of the 1 mg Overnight Dexamethasone suppression test is influenced by the use of oral contraception.2. Examen how many weeks after ceasing the use of orale contraception the 1 mg Overnight Dexamethason suppression test is…
Aim of the project is to determine whether it is possible to implement a CAT for the identification of children with psychosocial problems in Dutch JGZ. Additionally the study will evaluate the CAT as it is being used in practice. The trial…
To document cardiac function before and after treatment of CS.
What is the diagnostic accuracy of the schoolAMPS for children with DCD in the age of 6 to 11 year, compared to typical developing children in the same age, in the Netherlands? With diagnostic accuracy is meant: is it possible with the schoolAMPS to…
In the current study we will measure CVI in ASA 1-3 patients during elective abdominal surgery under fentanyl/sevoflurane/epidural anesthesia. We will monitor patient movement as primary correlate to CVA and cardiovascular parameters as secondary…
Determine wether or not a strategy based on molecular analysis is effective in improving the PFS
The aim of this study is to compare the sensitivity of chromoendoscopy with Lugol*s solution with conventional white light video endoscopy in diagnosing esophageal dysplasia and cancer in patients with achalasia.
This project aims at evaluating the reliability, validity, and the added value of the SDQ (Parent Format ) compared to LSPPK (a Dutch questionnaire to detect psychosocial problems in toddlers and children). The study findings may support the Dutch…
Objective: Evaluation of the supposed correlation between increased serum and urine NGAL levels (> 350 ng/ml) and significant increases in serum creatinine levels in adult ICU patients compared to preclinical levels
The general aim of this study is to explore how a motivational deficiency (i.e. apathy) related to neurodegenerative diseases is associated with effort and how it can be distinguished from intentional underperformance. We will investigate whether…
The objective for this trial is to evaluate an invasive strategy using urgent PCI (<3h) as compared to an early PCI (24h) using novel quick acting antiplatelet therapy.
Primary Objective: Phase 1: Reproducibility To investigate the reproducibility of the LVVTCs of the HCP during exercise (cardiopulmonary exercise testing, CPX). Phase 2: Validation and association with physical fitness in healthy volunteers. To…
To determine the differences in muscular activity of the diaphragm between children with controlled asthma, uncontrolled asthma, dysfunctional breathing patterns and healthy children.
This project aims to assess whether the nutritional intake of Paralympic athletes meets their physiological demands. Therefore, we will investigate energy expenditure, dietary intake, body composition and bone health of disabled athletes, ultimately…
The primary objective of the study is to determine feasibility of CEA assessments at home using (automated) capillary sampling. Home based (automated) capillary sampling will be considered feasible if a success rate of 85% or greater has been…
The aim of this prospective one-year follow-up study is to investigate whether preoperative 3D US measurements of AAA characteristics with and without the use of a US contrast agent are comparable to CTA. The secondary objective is to identify…
Primary objectives: To determine and compare the diagnostic yield of two different methods (FaceReader technology and a deep learning model specifically developed for video data) to analyse facial weakness from video recordings (04:00m) with…
The overall objective for this study is to train and validate EsoGuard-based diagnosis characteristics