24 results
We hypothesize that sleep apnea screening, using a combination of an online questionnaire and high resolution overnight oximetry, can safely be applied to exclude sleep apnea with high sensitivity (≥97%) and acceptable specificity (≥60%) in patients…
Determing the relation between postoperative deltoid volume and clinical outcome following reversed shoulder arthroplasty after 2-13 years of followup.
Primary objective:• To assess the safety and feasibility of adding ipilimumab-nivolumab to a CRT induction protocol• To assess the efficacy of adding ipilimumab-nivolumab to CRT on the likelihood of a pCR and MPRSecondary objectives: • Local and…
Primary Objective: 1. To determine the non-inferiority of pre-hospital risk stratification and care path selection through the preHEART algorithm as compared to usual care with respect to the occurrence of unexpected serious adverse events (USAE) in…
Non-invasive localization of the origin of idiopathic ventricular arrhythmias
With this study we try to answer the following question:What is the clinical outcome after a corrective osteotomy of a forearm malunion when we virtually plan the correction preoperatively and whether or not use patient-specific guides…
To test the clinical efficacy of vibrating socks, a new tactile cueing device, for the management of FOG in patients with PD.
* To examine the effects and interactions of individual and environmental factors on the onset and course of mental health problems in adolescents and young adults. * To examine the effects and interactions of individual and environmental factors on…
To investigate whether adjusting the length of the BP-limb of the OAGB based on measured total small bowel length leads to more weight loss, resolution of co-morbidities with less development of micronutrient deficiencies and bowel movements…
We would like to investigate whether GOS benefically alters the microbiota composition and -activity of the colon (not only faeces as done previously). This has not been done before by performing colonoscopies in a physiological condition and…
The primary objective is to evaluate the effect of preoperative weight loss (by means of a 14-day low-calorie diet) on the operative time of the RYGB procedure. The first secondary objective is to evaluate the effect of preoperative weight loss on…
To investigate neural response patterns to visually and orally presented palatable (high vs low caloric) and unpalatable (high vs low caloric) foods in AN patients and matched healthy controls (HC). This will be investigated through 1 study with 2…
1. To unravel which factors (altered CPP, structural, functional, metabolic, inflammatory and psychological factors measured presurgical) are predictive for an unsatisfactory outcome 1 year after a primary TKR (longitudinal).2. To unravel the…
Our objective is to evaluatie the effect of an online, psychologist-guided intervention (eMBCT) on fatigue, stress and overall QoL in patients with sarcoidosis. Not only patient-reported outcomes, but also objective markers such as hair cortisol…
The aim of this multicenter open-label, randomized controlled trial is to investigate the superiority of 5 days (extended) versus a single dose of cefazolin prophylaxis in revision arthroplasty of the hip and knee.
To prove that omitting drains after mastectomy and flap fixation does not contribute to higher incidence of seroma formation and therefore reducing patient disutility such as seroma aspirations and visits to the outpatient clinic, as well as…
The main objective of this study is to look at the effect of iv acetate infusion on postprandial glucose metabolism and whether this effect differs between healthy lean subjects and obese subjects with metabolic syndrome.The secondary objectives of…
The primary objective is to assess the adaptive T cell response to VIT in HVA patients with underlying ISM (ISM+) after treatment induction (at thirteen weeks) and upon reaching maintenance dose, after seven months, in comparison to the baseline…
Primary Objective: * To evaluate the presence and time of occurrence of a niche in women who underwent a caesarean delivery Secondary Objective(s): * To evaluate changes of niche size and thickness of the residual myometrium over time* To determine…
Primary objective: Response to trametinib treatment defined as a tumor volume decreases from baseline of >=20%, monitored by using volumetric MRI analysis. Secondary objectives are: patient reported outcomes of pain and disability and quality…