406 results
Conditions that promote IL-10 producing B cells in humans are still ill defined. In this project our aim is to investigate the frequnecy of IL-10 producing B cells in healthy volunteers. Next, we aim to compare this to the frequency of IL-10…
To assess whether preoperative radiotherapy, as an adjunct to curative-intent surgery, improves the abdominal local recurrence-free survival.
(1) To determine frequency of antibody-mediated encephalopathy in adults with new-onset epilepsy/status epilepticus or chronic epilepsy. (2) To assess outcome of antibody-mediated encephalopathy in adults with epilepsy, and identify markers for good…
To study sensory processing and hyperexcitability in children with ASD and epilepsy using neurophysiological measurements (EEG/ERP).
The main objective of this study is to assess whether ICD therapy in dialysis patients reduces sudden (arrhythmogenic) cardiac death. The first secondary end point is to compare total mortality death between the two groups. An other is to evaluate…
The next questions will be addressed in the present study: 1. Do moderately preterm infants differ in development and attention and concentration capacities from a term and very preterm infants during the first years of life? 2. Do attention and…
The primary objective of the study is to evaluate the effect of diuretics on right ventricular function and volume properties in patients with symptomatic right heart failure and PH.
The main objective of the panel study is to evaluate the associations between short-term variation of concentrations of key air pollutants (NO2, PM2.5, PM10, and ultrafine particles), measured on a fine spatial and temporal resolution, and short-…
The primary objective is to determine the efficacy of a disease specific cognitive behavioral therapy program in adolescents with IBD and increased symptoms of depression or anxiety on reducing symptoms of depression. Secondary objectives are to…
The goal of this study is to better characterize the metabolic alterations and sugar structure alterations (glycosylation abnormalities) in patients diagnosed with Congenital Disorders of Glycosylation.
EXPLICIT aims tot obtain better functional outcome by early intensive rehabilitation. Next to clinical tests to measure improvement in function, neuroplasticity is assessed by fMRI, TMS and haptic robots. The combination of clinical outcome measures…
Primary: Progression free survival.Secondary: Toxicity, overall survival, response rate, duration of response, translational research.
We want to compare duplicate measurements of celite ACT and kaolin ACT in patients undergoing cardiac surgery. In addition we want to measure heparin use during surgery in patients monitored with celite ACT and with kaolin ACT.In addition,…
What is the effect of image magnification on straylight values and is there a correlation between change in straylight values and change in visual acuity after pIOL (Artisan/Artiflex) implantation.
Overall, our primary research goal is to elucidate the underlying molecular and cellular neurobiology of depression. Specifically, this study will focus on the following key objectives:1. My first objective is centered on the major prevailing…
To investigate the use of a temporary peginterferon alpha-2a add-on strategy during entecavir therapy in patients with HBeAg-positive chronic hepatitis B by comparing the efficacy of this regimen versus entecavir monotherapy.To evaluate the long-…
The objective of this multicenter prospective observational study is to estimate in a follow-up period of 2 years the cumulative incidence of metastases in OTR with cutaneous invasive SCC. In addition we will estimate the contribution of risk…
To demonstrate differences in neuronal structure and neuronal function in brain regions that control eating behaviour between obese and normal weight adolescents.
This study aims to gain more insight in the sexual development of adolescent boys with ASDs.The main research question is: How do high functioning boys with ASD develop sexually? The main research question is worked out in 2 parts/1. Which sexual…
The purpose of this study is to contribute to the knowledge of feeding problems in infants with CL, CP and CLP. Our evidence based results can help clinicians, involved in the care of cleft patients, in providing proper information and professional…