62 results
We aim to fill up the present gap in knowledge about HCO3- and mucus transport in native human intestine, and about possible effects of pharmacological correctors on these parameters in CF, by detailed electrophysiological and biochemical ex vivo…
The objectives of this study are:1. to evaluate the occurrence and distribution of structural brain changes in HHT patients with and without pulmonary AVMs as compared to healthy age matched controls;2. to evaluate the (autoregulatory) function of…
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What is the effect of image magnification on straylight values and is there a correlation between change in straylight values and change in visual acuity after pIOL (Artisan/Artiflex) implantation.
The objective of this multicenter prospective observational study is to estimate in a follow-up period of 2 years the cumulative incidence of metastases in OTR with cutaneous invasive SCC. In addition we will estimate the contribution of risk…
Research QuestionWhat is the long-term effectiveness and cost-effectiveness of self-management support via an internet based service in addition to usual care as compared to usual care alone in patients with COPD who have completed pulmonary…
To study the effect of compression stockings during supine and head up tilt on cardiac stroke volume as a reflection of the changes in central blood volume.
The Objective of this study is to validate the new developed sensor fotoplethysmografie (MPA-16), that later can be used to better understand the local vasculature. And determining the feasibility / applicability of this test setup for patients.
Primary Objective: To evaluate cytokine levels in blood samples of human subjects with tinnitus and normal hearing, compared to healthy controls.Secondary Objective(s): To evaluate complete blood count measures (neutrophil count, platelet count etc…
Investigation of the performance of the Virax Immune COVID-19 kit when tested using blood donations from healthy participants.
To compare the appearance of dietary protein-derived amino acids in plasma after ingestion of a milk protein powder with different levels of protein glycation in healthy young men.
Primary objective:• To investigate the efficacy, defined as clinical benefit (stable disease (SD), partial response (PR), complete response (CR)) at 12 weeks, confirmed on a second scan after 4 weeks, of an FMT-intervention with responder and non-…
Does isolated cup revision surgery or liner exchange through the anterior approach result in increased functional status and higher patient satisfaction than through the posterolateral approach?
The primary objective is to develop a disease model predicting clinical meaningful changes based on a combination of results of tests on clinical function, muscle MRI, echocardiography and circulating biomarkers applicable in various stages of…
To compare health-related quality of life, specifically fatigue, in melanoma patients treated with immunotherapy who use or do not use a patient-centered mobile coaching and monitoring system (CAPABLE). We expect that by using the CAPABLE eHealth…
Primary: to determine the loss of corneal endothelial cells after implantation of a Paul GDD with its tube either anterior or posterior of the iris. Secondary: to compare efficacy and safety of both procedures.
1. Assess the effect of Ru-106 brachytherapy applicators on tumor dimensions. 2. Assess the value of DWI and PWI as an early predictor of therapy response after Ru-106 brachytherapy in UM.
What is the clinical- and cost-effectiveness of early low-dose oral immunotherapy aimed at long-term tolerance induction in children under the age of 30 months with an established food allergy compared to routine care?What is the effect of early low…
The aim of this study is to demonstrate that accurate brain stimulation is possible in anatomical location and timing.
This project aims to determine the effectiveness of two reading interventions: Vistra and Rotated Reading. The effects will be investigated on the level of functions, activities and participation. A nuanced view will be provided as to which training…