63 results
The primary objective of this study is to demonstrate that free field word recognition scores in quiet and noise with CI *ON* are significantly better than the best aided pre-implant scores in the ear to be implanted (contralateral ear plugged)…
Overall, our primary research goal is to elucidate the underlying molecular and cellular neurobiology of depression. Specifically, this study will focus on the following key objectives:1. My first objective is centered on the major prevailing…
The prime objective of the IMPROvED project is to develop a clinically robust predictive blood test for pre-eclampsia, using innovative technologies and utilising novel metabolite and protein biomarkers. This blood test is targeted to all first time…
To assess the one-year (cost)effectiveness of telemonitoring of blood pressure and self-management support via an internet-based service in addition to usual care as compared to usual care alone in a pragmatic trial in patients with uncontrolled…
1) to gain insight in the pathophysiological mechanisms leading to intellectual disability and 2) to create a model system which allows screening of therpeutic interventions for efficacy.
We aim to determine an association between the presence of complement binding anti-paternal HLA-C antibodies and preeclampsia.
Primary Objective• To demonstrate feasibility of measuring deuterium incorporation into galactosylceramides within the quantitation limits of the assay, in human CSF after chronic dosing of D2O.• To develop a mathematical model to allow estimation…
Objective: The primary objective of the study is to determine whether the intracervical installation of vasopressin reduces the incidence and severity of gas embolism as detected by trans oesophageal echocardiography (TOE…
Primary Objective: To evaluate cytokine levels in blood samples of human subjects with tinnitus and normal hearing, compared to healthy controls.Secondary Objective(s): To evaluate complete blood count measures (neutrophil count, platelet count etc…
Investigation of the performance of the Virax Immune COVID-19 kit when tested using blood donations from healthy participants.
To compare the appearance of dietary protein-derived amino acids in plasma after ingestion of a milk protein powder with different levels of protein glycation in healthy young men.
Primary objective:• To investigate the efficacy, defined as clinical benefit (stable disease (SD), partial response (PR), complete response (CR)) at 12 weeks, confirmed on a second scan after 4 weeks, of an FMT-intervention with responder and non-…
Does isolated cup revision surgery or liner exchange through the anterior approach result in increased functional status and higher patient satisfaction than through the posterolateral approach?
The primary objective is to develop a disease model predicting clinical meaningful changes based on a combination of results of tests on clinical function, muscle MRI, echocardiography and circulating biomarkers applicable in various stages of…
To compare health-related quality of life, specifically fatigue, in melanoma patients treated with immunotherapy who use or do not use a patient-centered mobile coaching and monitoring system (CAPABLE). We expect that by using the CAPABLE eHealth…
Primary: to determine the loss of corneal endothelial cells after implantation of a Paul GDD with its tube either anterior or posterior of the iris. Secondary: to compare efficacy and safety of both procedures.
1. Assess the effect of Ru-106 brachytherapy applicators on tumor dimensions. 2. Assess the value of DWI and PWI as an early predictor of therapy response after Ru-106 brachytherapy in UM.
What is the clinical- and cost-effectiveness of early low-dose oral immunotherapy aimed at long-term tolerance induction in children under the age of 30 months with an established food allergy compared to routine care?What is the effect of early low…
The aim of this study is to demonstrate that accurate brain stimulation is possible in anatomical location and timing.
This project aims to determine the effectiveness of two reading interventions: Vistra and Rotated Reading. The effects will be investigated on the level of functions, activities and participation. A nuanced view will be provided as to which training…