153 results
To investigate the association between shear stress and plaque growth and plaque composition changes over time. Furthermore, it will be investigated how these plaque changes influence the local wall stress.
Primary Objective: Pilot study to identify the optimal patch test concentration for detecting contact allergy to ME-PPD in subjects with a proven contact allergy to PPD, who may be allergic to ME-PPD. Hypothesis: In this study subjects will be…
to determine the percentage of patients with CKD, without a history of gout or attacks of arthritis, that have tophi measured by US,DECT and clinical examination. to determine the percentage of patients with CKD, that have tophi measured by US, and…
The objectives of this study are:1. to evaluate the occurrence and distribution of structural brain changes in HHT patients with and without pulmonary AVMs as compared to healthy age matched controls;2. to evaluate the (autoregulatory) function of…
To compare accumulation of liver fat (as measured using CAP) and liver fibrosis (as measured using fibroscan) between patients with quiescent and active inflammatory bowel disease
The overall aim of the study is to improve diagnostic and therapeutic options for people with CF, especially in the context of young children and novel CFTR-targeting drugs. Primary Objective: 1. to demonstrate relations between CFTR genotype,…
The primary objective of this study is to determine the Optical Density Ratio (ODR) for the prototype CORIMAP camera and compare the ODR values with the Oxymap T1 mounted on a regular fundus camera in a healthy adult population. For comparison, it…
To further optimize 7.0 Tesla MRI techniques and to develop new MRI techniques that will enable state-of-the-art clinical and cognitive research leading to improved patient care. Whereas some applications of 7.0 Tesla MRI already show improvements…
To identify novel diagnostic and prognostic (bio)markers of Dementia with Lewy Bodies.
To evaluate whether blood CC12gene expression defines disease status (Stage I-IV, stable or progressive) and whether the blood CC12gene expression predicts response to therapeutic intervention.
Our primary objective is to identify the disturbances in prosody, phonation and articulation with which dysarthria can be automatically recognized in speakers of Dutch, and German. To this end, we will first perform an experiment that involves the…
The prime objective of the IMPROvED project is to develop a clinically robust predictive blood test for pre-eclampsia, using innovative technologies and utilising novel metabolite and protein biomarkers. This blood test is targeted to all first time…
To investigate whether high resolution multi-site epicardial mapping of the atria in patients with structural heart disease undergoing cardiac surgery can identify patients at risk for developing early post-operative atrial fibrillation. The…
The objective of this study is threefold:1) compare the effectiveness and cost-effectiveness of brief CT added to maintenance AD versus maintenance AD alone versus guided tapering or discontinuation of AD with brief CT.2) examine whether the…
- assessment of age dependent reference values (ages 20 - 70 yrs) for plasma renin (activity and concentration), serum aldosterone and 24h urinary aldosterone (free and metabolites) during a regular diet and after a 3 day oral salt loading test-…
To explore the role of 4D PET-CT in radiation treatment planning, relative to standard 3D PET-CT.
To determine the effect of a single red blood cell transfusion on the microcirculation.
Intermittent neurogenic claudication due to lumbar stenosis is frequently diagnosed among older persons. Due to an aging population it is to be expected the incidence of lumbar stenosis will increase over time. Patients are operated on because of…
The aim of this study is to estimate the prevalence of late-onset inherited Pompe disease in a large cohort of patients with recently diagnosed obstructive sleep apnea syndrome (OSAS) in two different centres across Europe.
The purpose of this study is to improve the diagnosis and management of hepatocellular adenoma.