58 results
1. Are there differences between patients and controls in circadian movement rhythmicity and sleep duration?2. Are these objective measures associated with subjective sleep complaints?3. Are these objective measures associated with decreased quality…
Does HLA sharing in couples with recurrent miscarriage play a role in recurrent miscarriage of unknown etiology?
Assessment of the cutaneous and retinal microcirculation in SCD patients and matched controls:- Long- and short-term repeatability of LSCI and NiRFI ;- Comparison of cutaneous and retinal microcirculation between SCD patients and matched healthy…
To understand, from the perspective of the 3-hit hypothesis of psychopathology, individual differences in the neuropsychiatric outcome of previous glucocorticoid (GC) excess in treated Cushing patients.
• To investigate if FD in CRPS is associated with specific structural and functional changes of the brain.• If so, to find out which of these changes are specific for FD in CRPS, i.e., independent regardless the clinical setting (pain versus…
To study the effects of transient severe endogenous stress hormone exposure on the structure and functioning of brains circuitry regulating emotion, and the association with cognition and psychopathological symptoms.
Objectivesi)) To study whether reproductive hormones play a role in migraine susceptibility in malemigraine patients; ii) to study functionality of the trigeminal system prospectively duringinterictal and premonitory phases of the migraine attack (…
The goals of the present study, therefore, are twofold:a) To estimate the incidence of dream/reality confusions in the narcoleptic population, relative to healthy controlsb) To provide a comprehensive description of the characteristics of these…
To answer the following research questions:How is quality of life in patients with adrenal insufficiency?How is cognitive functioning in patients with adrenal insufficiency?Is there a difference in cognitive functioning between patients who did/did…
The main objective of this proposal is to request permission for recruitment and participation of individuals between ages 8 and 30 in an fMRI session and several behavioral testing sessions. These studies are aimed at relating brain development to…
to find evidence for frontal inhibition during planning of explicit movements just as seen in patients with conversion disorders.
Performing this experiment will give proper insights in nutrient sensing after nutrient intake in normal cells. The feasibility of measuring these nutrient sensors and the potential of ensuring sufficient quantity of lymphocytes will be explored.…
The objective of the current proposal is to further explore the pathophysiological changes that occur in patient with an IGSF1 mutation, using an established method for assessing hormone secretory characteristics.
In this project, I wish to take a novel step in understanding the influence of environmental exposures in the aetiology of psychotic disorders, by studying occurrence of (minor) psychotic symptoms and the (correlates of) physiological indicators of…
Social and emotional functioning of hearing impaired children, in the agegroup between 9 and 15 years old.
The aim of the present study is to investigate cerebral vasoreactivity in response to lower body negative pressure in young and elderly healthy men, as a measure of cerebral autoregulatory responsiveness.
The aim of the represent proposal is twofold, 1. [PHASE 1] the establishment of a human tissue biobank including muscle and blood, and additionally from a subset subset of subjects fat and skin biopsies will be taken. Samples will be distributed…
1. Assessment of sensitivity of several outcome measures in muscle force and function in Duchenne muscular dystrophy2. Assessment of reproducability of different outcome measures3. Assessment of clinical relevance of measured change over time in…
To study the possible beneficial effect of simvastatin on accumulation of triglycerides in the myocardium of patients with DM2 and the effect on vessel wall thickness using magnetic resonance imaging and spectroscopy
What values are normal in healthy controls for endurance and force? Are these values the same for men and female? What is the effect of age to these normal values? What are endurance and force for patients with myasthenia gravis? Are there specific…