166 results
In patients diagnosed with a hip fracture who also have acute myocardial injury on presentation to hospital, is accelerated surgery superior to standard care for the primary outcome of death at 90 days after randomization?
This study has been transitioned to CTIS with ID 2023-506604-18-00 check the CTIS register for the current data. Primary:- To evaluate the safety and tolerability of SGN-PDL1V in subjects with advanced solid tumors.- To identify the maximum…
This study has been transitioned to CTIS with ID 2023-509707-32-00 check the CTIS register for the current data. To investigate whether the response rate of pembrolizumab exceeds the response rate of the historic control in locally advanced,…
This study has been transitioned to CTIS with ID 2023-507069-25-00 check the CTIS register for the current data. The primary objectives for the study are: Cohort 1, to characterize cardiac safety of different Daratumumab, cyclophosphamide,…
To demonstrate that removal of drains exclusively based on digital drainage system data is non-inferior to additional clamping trials regarding recurrent pneumothorax requiring chest tube reinsertion.
We aim to investigate the relationship between positive schema activation and subsequent tests of emotional schema memory, and whether tDSC during positive schema activation can facilitate retrieval of emotional memory for positive information in…
To evaluate in SSc patients with low risk for disease progression 1) whether assessment in an outpatient clinic setting is an acceptable alternative for evaluation in the Care Pathway. Outcome parameters we will evaluate include 1) health care…
This study has been transitioned to CTIS with ID 2023-505483-11-00 check the CTIS register for the current data. To investigate if early transition to oral treatment after two weeks or longer of IV antibiotic therapy is non-inferior to standard six…
Predict response to FOLFIRINOX treatment in patients with LAPC based on baseline stiffness values derived with MRE.
To investigate whether VR-VOICES is more effective than regular treatment for voicehearing in patients with auditory hallucinations.
The main goals of this study are to study the effects of VHPSD ablation on the duration of a pulmonary vein isolation procedure, and on transient (edema) and persistent (fibrosis) effects of VHPSD ablation in the left atrial wall.
This study has been transitioned to CTIS with ID 2023-505645-12-00 check the CTIS register for the current data. Main objective: To evaluate the efficacy of BIIB122 225 mg compared with placebo.Secondary objective: To evaluate the efficacy, safety…
The main objective of this study is to assess the effectiveness of an integrated program of fitting and training interventions aimed at reducing unexpected variability and addressing the specific error patterns of each recipient.
Comparing different ventilation strategies in focal and non-focal ARDS in invasively ventilated patients admitted to the intensive care unit.
Primary aim: To establish reference values for exercise-induced elevations of cTn concentrations following walking, cycling and running exercise. Secondary aim: Assess the prevalence of (sub)clinical coronary artery disease in individuals with high…
Implement BBB-ASL at VUmc and assess the reliability and reproducibility of f measurements in healthy volunteers and patients with glioma
Objective: Evaluate uterine contraction features (frequency, amplitude, direction, and coordination) using a dedicated speckle-tracking algorithm by 2D transvaginal ultrasound measurement in postmenopausal women presenting with vaginal bleeding or…
Through the utilization of fMRI and DUS we aim to illustrate the physiological change a kidney graft undergoes during a transplantation trajectory from donor to recipient. Secondarily, we intend to establish a baseline reference for normal…
The purpose of the current study is to test the effectiveness of both trainings (IBT and ABT) in a non-clinical and clinical sample, with the future goal of making the training available to all patients with BPS. The central objectives for this…
Lifestyle intervention programs reduce inflammatory activity and might, therefore, be of added value in the management of patients with an inflammatory arthritis. Therefore, the aims of this randomized controlled trial are: 1. To compare the…