18 results
An information campaign was developed targeting early-stage KHOA patients and healthcare professionals (HCPs) to optimise timing of referral to secondary care.
The primary goal is to investigate whether controlled dose reduction of IL17 or IL23 inhibiting biologics is not inferior compared to usual care. This is measured by comparing the proportion of long-term disease flares between the two groups (dose…
The aim of this study is to investigate the feasibility and safety of a 23-hour accelerated ERAS protocol for patients undergoing colorectal surgery. In this accelerated ERAS protocol, patients undergoing colorectal surgery will be discharged within…
Primary Objective: Investigate whether EMDR Flash Forward is an effective intervention to process the mental images of worst case scenarios that occur in paranoid delusions, in order to decreases the preoccupation with the delusion.Secondary…
To evaluate the performance of the newly-developed prosthesis (prototype) during walking in people with a transfemoral osseointegration implant. This will be done using lab-based measurement, evaluating metabolic cost, walking capacity, gait pattern…
The current study aims to elucidate neural correlates of pain processing and dissociative analgesia in PTSD. To this end, we want to replicate the pilot study by Mickleborough et al., (2011) and test the functional pain processing protocol with…
The aim of this study is twofold: 1) to measure ROTEM profiles in patients at risk for DIC to determine cut off values of ROTEM corresponding to the currently used International Society for Thrombosis and Haemostasis (ISTH) DIC scores, as well as to…
The current study is an initial evaluation of the feasibility and effects of exposure therapy in those suffering from ED and comorbid PTSD.
To compare automated closed-loop ventilation (INTELLiVENT-ASV) to conventional, non-automated ventilation in patients in the ICU.
• To evaluate the effect of palliative sedation on patients comfort and other symptoms in different international hospices, palliative care units and hospital ward settings.• To assess the clinical practice of palliative sedation in different…
Evaluation of the effects of a integrative lifestyle intervention program on health related quality of life after ICU-admission.
The main objective is to investigate the fixation of the Journey II XR BCR TKA in terms of micromotion of the femoral and tibial components over time measured by RSA. Secondary, this study aims to assess the effect of this BCR TKA on daily life…
The aim of this study is to validate the accuracy of SNNS for the detection of tumor-positive LNs using lymphoscintigraphy with radioactive tracer and NIR with ICG in patients with early EAC with regional LN involvement (clinically staged as T1N1).
We aim to demonstrate that robot-assisted laparoscopic radical hysterectomy is non-inferior to conventional laparotomy in recurrence free survival of patients with early stage cervical cancer (stage 1B1, 1B2 and 2A1).
To investigate the accuracy and effectivity of a short non-invasive fluid-sensitive MRI to identify clinical arthritis in patients with recent onset hand(s) complaints.The purpose of the *amendment* is to investigate in patients with joint…
In preparation of a randomized controlled trial, we aim to assess pilot data on technical feasibility and safety of LITT and to assess practical feasibility of a randomized study in patients with primary irresectable glioblastoma, as compared with…
This study has been transitioned to CTIS with ID 2024-516781-10-00 check the CTIS register for the current data. Primary objective:• Systemic immunogenicity of the DCP-001 vaccination in high grade serous ovarian (HGSOC) cancer patients.
Primary: To determine the efficacy and safety of bel-sar compared to sham control for thetreatment of primary indeterminate lesions and small choroidal melanoma (IL/CM).Secondary: To assess the systemic pharmacokinetics (PK) and immunogenicity of…