34 results
Concordance between MET diagnosis with and without the use of ultrasound with the chart review definitive diagnosis will be studied. Also other secondary endpoints will be evaluated.
To evaluate tailoring components in a web application for THA patients and to refine guidelines for tailored web applications for patients.Secondary objectives:- To assess how and how often THA patients use a prototype of the tailored web…
Primary objective: The primary objective of this study is to assess the effectiveness and cost-effectiveness of the Transmural Trauma Care Model (TTCM) as compared to usual care.The research question addressed is:Is the Transmural Trauma Care Model…
This study has been transitioned to CTIS with ID 2024-515825-27-00 check the CTIS register for the current data. To investigate efficacy of neoadjuvant axitinib and avelumab in patients with localized renal cell carcinoma with moderate to high risk…
The primary objective is to investigate whether polytrauma patients (Injury Severity Score [ISS] >= 16) admitted to the ICU who have or develop malnutrition have a higher complication rate than patients who are and remain well-nourished.…
Knowledge about which scanning behaviour is optimal, however, is mostly based on experiences and assumptions of professionals, and not supported by scientific literature and empirical data. Innovative techniques such as eye-tracking and Virtual…
The primary objective is to examine whether changes over time in monitoring measures of cognition and behavior are associated with functional outcomes in pediatric oncology groups. Additional objectives are to examine trajectories, risk factors, and…
Primary: To determine the feasibility of measuring muscle strength at home with the fixed dynamometerSecondary: Determining the sensitivity of the fixed dynamometer to detect changes in disease progression in ALS during home measurement
To survey the clinical and biochemical characteristics of individuals diagnosed with OCTN2, CPT2, CACT or BKT deficiency or suspected with OCTN2 deficiency after NBS in the Netherlands to aid the decision on whether or not to include these disorders…
In the STudying Ageing in Rheumatic diseases (STAR) project, our main goal is to: study the ageing process in patients with and without RA and specifically assess the impact of ageing on (1) the interpretation of commonly used measures of disease…
OpACIN-neo:Primary objectives: - To compare safety (immune related adverse events during the first 12 weeks) of three different neo-adjuvant combination schemes of ipilimumab + nivolumab - To compare radiological and pathologic response rates at…
The aim of this study is to test the hypothesis that continuous wireless monitoring on the postsurgical ward will improve patient outcome, measured as disability-free survival at three months after surgery. Further, we hypothesize that this tight…
To determine the effects of the PCP+SM compared with usual care on BP control in adults with hypertension. To determine the effects of the PCP+SM compared with usual care on antihypertensive medication use in adults with hypertension. To determine…
The objective of this study is to assess the non-inferiority of an internet-based HIV PrEP-service and reduced frequency of monitoring visits in comparison to standard-of-care at the GGD.
The main aim of the LOFIT study is to determine the (cost) effectiveness of a hospital-based dedicated LFO in comparison with usual care 12 months after participation
To describe physical activity level before and after CRT implantation and to explore factors related to the intention of patients with HF for implementing behaviour change (improve activity level). We want to collect this data to plan future…
Primary objective: To investigate if the presence of aneurysm wall enhancement predicts aneurysm instability in the long-term. Secondary objective: To investigate if the absence of aneurysm wall enhancement predicts aneurysm stability in the long…
Examining the applicability of a fieldable serological point of care serological test Biozek and Point of care molecular Fluorescent in Situ Hybridization (FISH) technology by Biotrack for the usage of decision making, containment and management of…
1. to monitor how seroconversion rates of SARS-coV progress during the COVID-19 pandemic in health care workers with direct contact with COVID-19 suspected or confirmed patients compared to a control group without this exposure, and 2. assess the…
Primary objectives: - To assess safety and feasibility of neoadjuvant nivolumab +/- domatinostat +/- ipilimumab- To identify pathologic response rates of nivolumab +/- domatinostat +/- ipilimumabSecondary objectives: - To describe all grade…