41 results
In this trial we will study if treatment with oral corticosteroids or DMSO is effective in decreasing signs and symptoms of CRPS-1. Tolerance of the treatment options and effects on different subtypes of CRPS-1 patients will be evaluated as well.
To select targeted treatment based on ex vivo kinase activity inhibition profiles to targeted agents of tumor tissue from patients with advanced cancer for whom no standard treatment is available.
To establish the performance of the idi-CGM system among persons with DM.
To test whether tACS in a theta frequency enhances extinction of physiological stress responses to exposure to anxiety- or trauma-related stimuli or memories. Secondarily, to examine the influence of baseline neuroendocrinological response, baseline…
The objective of this study is to evaluate the safety and effectiveness of the PerQseal Elite vascular closure system when used to achieve haemostasis of common femoral venotomies created by 14 to 22F sheaths (venotomy up to 26F) in patients…
This study aims to provide insights into the processes and key host immune and microbiota factors that determine the infection kinetics, transmission and development of immunity during such infections. Furthermore, this study will enable us to…
To investigate whether implementation of a best practice program for preoperative optimisation of patients with a focus on screening, assessment, and intervention of 8 potentially (partly) modifiable risk factors (low (aerobic) fitness level,…
The aim of this study is to establish the accuracy of Molecular Culture for prediciting the outcome of the traditional blood culture.
Objectives:The main objective will be to assess whether treatment with nVNS, LXB or both interventions will increase the clearance of Aβ from the brain, compared to pre-treatment, in patients with CAA. Second objective is to study whether CAA…
To evaluate whether the RBCs derived from WB and processed with the Reveos system using the non-DEHP disposable sets meet the US criteria for 24-hour recovery after 42 days of storage.
The primary objective is to evaluate the accuracy of the SpO2 measurements by the ViQtor compared to matched SaO2 measurements obtained during a hypoxic measurements to obtain the root mean square (ARMS) for a range of skin types defined by…
To investigate the effect of distracted consumption on glucose variability in women with GDM and to investigate moderating effects of type of distractor and perceived stress.
1. To generate initial data on whether a penile epithesis (ElatorTM) is a potential alternative to a penile prosthesis (ZSITM 475 FtM) in post-phalloplasty transgender individuals. 2. To assess participcant and partner expectations and experiences…
The Check@Home consortium aims to set up a roadmap and infrastructure for a (cost-)effective program to early detect atrial fibrillation and chronic kidney disease (defined by elevated albuminuria) in the general population. Furthermore, the project…
The primary objective is to perform a clinical validation of dried blood spot microsampling of imatinib, dasatinib, nilotinib, gilteritinib, midostaurin, and venetoclax. The secondary objective is to test the feasibility of home monitoring (…
Main objective: Develop a protocol to reproducibly infect mosquitoes with blood from human study participants undergoing asexual blood stage CHMI with the P. vivax clone PvW1.Secondary objectives: Maximize mosquito infection rate with PvW1 by I)…
Primary objective1. Assess that FAF can visualize the irradiated retina effects at an early stage after Ru-106 brachytherapy and PBT. Secondary objective1. Assess if these FAF-images can be correlated to the treatment plan.2. Correlate the observed…
To capture changes in cortical excitability, by using VEP-EEG recordings at home, in the pre-ictal phase of a migraine attack to serve as an early marker for upcoming attacks.
Clinical validation of capillary microsampling with finger pricks for olanzapine. The validation method is performed in accordance with the EM guideline. In this process, the analytical methods are assessed for selectivity, carry-over, lower limit…
To investigate the influence of flucloxacillin treatment on CYP - and UGT substrate plasma concentration, to gain further understanding of potential clinically relevant drug-drug interactions with flucloxacillin.