32 results
To compare the efficacy of six cycles neoadjuvant PTC plus pertuzumab preceded by either three cycles of FEC-T plus pertuzumab or three cycles of PTC plus pertuzumab in HER2 positive breast cancerSecondary objectives• To describe the safety of the…
To investigate the hypothesis that women with uterine prolapse stage 2 or more treated by laparoscopic sacrohysteropexy will have equal or lower recurrence rate of prolapse compared to women treated by vaginal sacrospinous hysteropexy.
To assess the outcome and pattern of frontal cognitive deficits between patients with cerebellar stroke compared to frontal stroke after three months of acute ischemic stroke with several validated neuropsychological tests and questionnaire
This study has been transitioned to CTIS with ID 2024-518355-36-00 check the CTIS register for the current data. Primary objective:- To determine the safety and optimal dose of three doses of a novel therapeutic vaccine (ISA104) consisting of 12…
This study has been transitioned to CTIS with ID 2024-518989-27-00 check the CTIS register for the current data. Objective: Primary Aim (PHASE 1):To determine the prevalence of RLS in women with ALD.Secondary Aim (PHASE 2):To determine whether in a…
Primary Objective: To evaluate whether KDT application as the KetoEasy meal plan induces ketosis and leads to seizure reduction in children 2-12 years with refractory epilepsy.Secondary Objective(s): To evaluate-Feasibility: application in daily…
To evaluate the safety, feasibility and efficacy of an 8-week remotely supervised home-based maintenance exercise training program following pulmonary rehabilitation in patients with COPD.
Primary Objective: - To establish the population range (24-h AUC) of high-dose infusional 5-FU in patients with locally advanced, resectable gastric or gastro-esophageal junction cancer treated with perioperative FLOT.Secondary objectives: - To…
The primary objective of the study is to evaluate the post-market safety and BMD improvement of AGN1 LOEP in patients with osteoporosis in at least one hip. The secondary objective is to evaluate the post-market functional measures of clinical…
The primary objective is to evaluate longitudinal developmental changes in brain structure in patients aged 6-18 years with SCD. The secondary objective is to analyze the longitudinal relations between biomarkers, demographic characteristics, brain…
Compare Atellica VTLi reference plasma separation membrane with at least one alternative plasma separation membrane using hs-cTnI values from capillary whole blood from fingerstick, Li-Hep whole blood and plasma from venipuncture.
The primary objective of DRAGON 2 is to demonstrate the superiority of combined PVE/HVE over PVE alone in either the resectability of the patients within 3 weeks after intervention defined as FLR sufficient for resection on week 3 and the 5-year…
The main objective of this study is to investigate whether access to a peer support platform, age-dependent information provision and games in a smartphone application increases self-reported quality of life, for children receiving a stoma.
The aim of this study is to find out how long the disease remains stable if we treat the 1-2 growing metastasis(s) locally by removing or irradiating/heating them, while continuing the treatment with your current drugs (anti-hormonal therapy,…
The objective of the study is to establish a data infrastructure to investigate the degree in which current and previous generations of young-old are characterised by healthy and successful ageing.
In this study, we aim to identify the diagnostic value of indocyanine green (ICG) fluorescence imaging for SLNBs via the mastectomy incision.
To determine safety and efficacy of low molecular weight dextran sulphate during islet transplantation
To observe and evaluate the efficacy, of Magic Touch SCB compared to one of the gold standard treatment for native vessel disease, (everolimus-eluting stent, EES).The main OCT subanalysis endpoints are:- Acute mean and minimum lumen cross-sectional…
This study has been transitioned to CTIS with ID 2024-517718-13-00 check the CTIS register for the current data. Primary Objectives:To determine the optimal dose of the VEGF-targeting optical agent Bevacizumab-IRDye800CW for an adequate tumor-…
To develop an innovative magnetic resonance imaging (MRI) protocol(M-ILD) for accurate phenotyping and sensitive monitoring of therapy in ILD patients.