675 results
To examine the effect of BCG vaccination on the composition and function of the bone marrow.
The primary objective is to determine the added effect of oral ondansetron to care-as-usual (including ORT) (CAU) on persisting vomiting within the first 4 hours after presentation at an out-of-hours primary care service (OHS) in children aged 6…
The primary objective is to assess the effect of the parenting support intervention on parental stress. Secondary objectives are the effect of theintervention on other parental outcomes (anxiety and depression, satisfaction with the parental role,…
This research will have as aim to look at progression or decrease of vascular calcification in dialysis population with use of different phosphate binders. There is a possibility that differect phosphate binders bind vitamin K in a different way in…
To determine whether early goal-directed therapy, aimed at optimizing cardiac output measured by arterial waveform analysis, improves outcome in high-risk, abdominal surgery.
Primary Objective: To compare the effects of hypothyroidism and hyperthyroidism on cardiac left ventricular function, as assessed by CMR, in subjects with differentiated thyroid cancer during their early treatment.Secondary Objective(s): To compare…
The main aim of the study will be to compare the urinary N-nitroso compounds levels after intake of 70 ml of concentrated red beetroot juice containing 400 mg nitrate either with or without supplementation with 1 g vitamin C.
To compare the functional outcome of ORIF with a volar locking plate to closed reduction and plaster immobilisation in patients with dislocated extra-articular distal radius fractures.
The objective of the study is to study the effect of Teripratide (rhPTH 1-34) on undercarboxylated osteocalcin levels, testosterone concentrations, glucose tolerance and insulin sensitivity in male subjects with primary osteoporosis.
1. Determine whether thrombo-elastography (TEG) the occurrence of postoperative blood loss and transfusions can predict after cardiac surgery.2. Determine whether platelet aggregometry (Multiplate and Verify Now) can predict the occurrence of…
The primary aim of this study is to find the dose of DHA during pregnancy and lactation that leads to a mean breastmilk DHA of at least 0.7g%.
Main objective: investigate the correlation between CAP-values with fat percentages found at 1H-MR Spectroscopy and steatosis grade at liver biopsy. Secondary objectives: investigate the reproducibility of CAP-measurements; investigate the…
The objective of this feasibility study is compare the smart AFO + standardized shoes to subjects* own AFO + own shoes. Subjects* experiences with the orthotic devices will be evaluated and points for improvement will be asked. Subjects* performance…
The main goal of this study is to validate the VR-game as a tool to provoke OCD symptoms and assess OCD symptom severity. The first objective is to investigate whether the VR-game is able to provoke OCD symptoms in OCD patients. The second objective…
To determine the long-term effects of meniscal allograft transplantation with regard to the radiological and patient related outcome (PRO), and the correlation between the two. The preoperative data of the MRI, Dual-energy X-ray Absorptiometry (DXA…
The primary study objective is to compare the efficacy, as assessed by overall survival, of surgery and neo-adjuvant chemotherapy to surgery alone in patients with resectable liver metastases of colorectal cancer and a high clinical risk score.…
PROFITS aims to improve prognostic models for functional outcome in a broad cohort of 160 stroke patients. PROFITS will:1) Uniformly assess determinants for recovery of functional outcome starting in the first week after stroke and functional…
We hypothesize that a smoking cessation strategy for smoking cervical cancer screening participants will increase their motivation to quit and will lead to an increased proportion of smokers performing a serious quit attempt. Eventually this will…
We investigated the safety and efficacy of on-demand SPG stimulation for chronic CH (CCH).
To unravel the cause(s) of the FH phenotype in patients with no mutations in well-established lipid genes (LDLR, APOB, PCSK9).