86 results
First objective; to document the existence and to categorize vocal fold pathology after short term intubation and to study voice related patient complaints after short term intubation. Second and third objective; to study the pattern/type of injury…
The aim of the present study is to establish intero-interoceptive fear conditioning in healthy participants in a differential conditioning paradigm. We want to make use of *real* interoceptive conditioned stimuli: a low respiratory load and small…
To analyze the relation between reduction in BMI and reduction in the exercise induced fall of FEV1 after a diet-period of 6 weeks. Secondary we analyze the relation between reduction in BMI and the recovery of the lungfunction to baseline (measured…
The general objective of HELIUS is to describe (trends in) patterns of chronic conditions across six ethnic groups over time, and to unravel the causes of (the unequal burden) of chronic diseases across ethnic groups, with an emphasis on…
The aim of the study is to investigate the local levels of steroid-hormones compared to the peripheral levels in postmenopausal patients with endometrial hyperplasia, endometrial carcinoma and postmenopausal women without these diseases. This will…
to measure peripheral insulin sensitivity and intramyocellular concentrations of different FA metabolites (ceramide, gangliosides, diacylglycerol and triacylglycerol) known to interfere with the insulin signalling cascade during infusion of…
The primary objective is to determine the effect of intravenously administered rhAPC on HDM-LPS induced allergic lung inflammation.
The objective is to study the effect of beta-agonist and beta-antagonist treatment on human bone remodeling.
The objective of this study to investigate the role of attention on the effect of NB on ad libitum intake.
To compare the levels of vitamin D in subjects with non-atopic asthma to those in subjects with atopic asthma and those in healthy non-atopic subjects
To test the following hypotheses:1. The baseline [123I]IBZM binding potential ([123I]IBZM-BP) in the ventral striatum is smaller in patients with SAHI than in healthy subjects, due to increased baseline activity of the mesolimbic dopamine system. 2…
Study 1: The objective of this study is to thoroughly characterize a large group of patients with non-atopic asthma clinically, functionally and with respect to inflammatory parameters and define 3-4 major phenotypes of this disease using unbiased…
This study focuses on visceral overweight and stress, related to intake of highly rewarding foods and food choice. The main objective of the study is determination of the effects of consumption of highly rewarding high protein/fat foods compared…
The goals of the proposed study are: (1) to further elucidate the relations between impulse control, motivational strength of drug cues, and brain activation patterns (using fMRI); (2) to examine the relative strength by which these processes are…
Idenification of new Hirschsprung's disease associated genes.
The objective of the study is to investigate the effect of alfa2-adrenoceptors on bone turnover.
The main objective of the study is to document cardiovascular dysfunction found in rheumatoid arthritis and gout patients using cardiac imaging techniques echocardiography and cardiac MRI.
1. What is the somatosensory profile of DM2 patients?2. What are the similarities and differences between the somatosensory profile of pain in myotonic dystrophy type 2 and fibromyalgia patients?
The primary aim of this study is to validate the paradigms designed to investigate the effects of social stress and reward on in healthy individuals. This will allow us to evaluate and optimize the experimental paradigms in terms of their design,…
1) To evaluate the feasibility and the acute effect of intra-operative cryoablation of the slow conducting anatomical isthmuses (endpoint bidirectional conduction block) and on the re-inducibility of monomorphic isthmus dependent VT. 2) To study the…