15 results
The overall aim of the current study is to improve quality of life in patients with cognitive disorders. First, by improving diagnosis of PTSD symptoms in these patients. Second, we will estimate comorbidity rate of PTSD in clinical populations of…
Evaluation of the effect of different treatment thresholds in a clinical pathway for children with acute asthma who are treated with supplemental oxygen
The objective of this prospective randomized controlled trial is to compare the outcomes of arthroscopic primary repair of proximal ACL tears with the current gold standard of ACL reconstruction.
To optimize (early) diagnosis and risk-stratification of (early) cardiomyopathy phenotypes and to create a better understanding of underlying pathophysiological processes.
The aim of this study is to assess the efficacy of MR-HIFU as a treatment modality for desmoid-type fibromatosis (DTF).
Primary Objective:To establish the maximum tolerated healthy liver-absorbed dose of 166Ho-microspheres in patients with HCC who receive RL as a bridge to resection.Secondary Objective(s): 1) To establish dose-response relationships between:a. The…
The purpose of the study is to test the feasibility of image-guided navigation during robot-assisted sentinel node dissection.
This study investigates how well the combination of the two drugs, zibotentan and dapagliflozin, works for the treatment of chronic kidney disease in patients. We compare the effect of zibotentan and dapagliflozin with the effect of a placebo. The…
Primary objective: To evaluate the role of existing and novel quantitative biomarkers in understanding the heterogeneity in the Parkinson*s phenotype (i.e. rate of progression, cognitive and neuropsychiatric impairment and motor dysfunction) and…
The main objective of this study is to determine the efficacy of STAIRS. The secondary objectives are: (1) to investigate the association between improved personal recovery and depression relapse and (2) to gather qualitative insights into the…
The main objective of this project is to build a comprehensive model for a better predictio n of progression in MS, as a first step to move towards personalized prediction. Secondary objectives aim to study specific aspects of underlying mechanisms…
The aim of this study is to determine the effectiveness of N-sleeve in terms of a reduction of GERD in morbidly obese patients, compared to LRYGB.
Primary objective:The objective of this randomized phase 2 study is to demonstrate efficacy of RE in terms of PFS in colorectal cancer patients with liver-only metastases who are candidates for palliative systemic treatment with capecitabine plus…
Primary objective • In this study we will investigate whether biochemical imaging of change (Δ, figure 1) in the metabolic phospholipid ratios of PME and PDE between baseline and after 2 weeks of therapy are predictive for progression free survival…
The main objective of this study is to investigate the acute beneficial effect of moderate inten-sive exercise (defined as walking) on neurocognitive functioning in healthy children and adults with mild CP, GMFCS I and II and if this effect is…