53 results
The aim of this study is to evaluate the validity of various algorithms for gait bout detection and spatiotemporal measures with a 3-IMU based sensor set worn on the feet and lower back. If this algorithm can be validated, it can be used to obtain…
Assessing the effects of SCS in patients with mononeuropathy measured according to the IMMPACT guidelines (pain reduction, improvement of quality of life, physical and emotional functioning, medication use, adverse events), and assessing the…
To investigate the production of sufficient numbers of effective CAR/CCR T-cells with T-cells obtained from blood of MM patients.
Primary Objective:1. Turnover rate of antigen-specific cells (group I)2. Turnover rate of functional T-cell subsets (group II)Secondary Objective(s):• Determining absolute numbers of antigen (poliovirus, measles, Hepatitis A and Hepatitis B)…
To develop a FOG prediction algorithm under free-living conditions, and to test evaluate the use of the Parkinson's Vibrating socks under the same conditions
The prognostic accuracy of combining these four criteria to predict the later development of personality disorders (with/without psychosocial breakdown) is investigated in a longitudinal study. From this, a selection of items with the strongest…
The ultimate objective is to optimize pessary treatment for all patients with pelvic organ prolapse (POP). To reach this goal, we need to learn more about the mechanisms behind success and failure of pessary treatment. Previous research suggested…
1. To identify the perceived barriers and facilitators for initiating and maintaining a healthy lifestyle in people with both DM2 and a low SEP. 2. To co-create a digital, personalised CBT lifestyle tool together with end users (people with DM2) to…
The objective of this study is to evaluate the insulin delivery of the Medtronic Implantable Insulin Pump System (MIIPS 2020).
Primary Objectives:Associated pharmaceutical trial:To compare the efficacy of disitamab vedotin in combination with pembrolizumab to chemotherapy as first-line treatment in participants with advanced UC that expresses HER2Clinical…
To obtain the best filling pressure of the Pes catheter in spontaneous mechanical ventilation, to obtain the esophagus elastance in spontaneous mechanical ventilation, and to compare the best filling pressures between the two modes (spontaneous and…
Primary ObjectiveTo assess the safety, feasibility and frequency of relapsing P. vivax PvW1 infection after experimental sporozoite-administered Controlled Human Malaria Infection (CHMI)Secondary ObjectivesTo assess the immune response to primary…
The aim of the current study is to determine the transport functionality, integrity, and viability in intestinal tissue obtained from patients who are expected to have a disturbed intestianl functionality due to severe obesity.
The aim of this study is to assess the position and alignment of the Atlas, as measured by the angles between the atlas and the surrounding vertebrae in healthy participants, patients with tension headache, and patients with chronic whiplash-…
Primary objective* To determine the extent to which muscle strength is affected in patients with RYR1-RM with autosomal dominantmutations and describe measurements over time.Secondary objectives* To determine the extent to which fatigue and…
The general aim of this project is to determine the (cost-)effectiveness of footwear modification in addition to GP-led usual care, compared to GP-led usual care alone for patients with first MTP joint osteoarthritis (OA) at 6 months of follow-up…
The objective of this study is to accumulate clinical data on the safety and performance of NBGM200 embolization in patients with degenerative OA of the knee refractory to conservative treatment so as to provide evidence of conformity with…
To assess the impact of a nutritional formulation containing caprylic acid and omega 3 fatty acids on skeletal muscle function recovery from damaging exercise.
Primary objectives1. To determine the effect of a tailored exercise program by using the widely implemented exercise app *Physitrack* on experienced pain and fatigue in patients with FSHD.2. To investigate the relationship between perceived pain…