135 results
The primary objective is to measure the dose of cerebral ischemia, as a measure of cerebral hypoperfusion, before, during and after aortic arch surgery. Secondary objectives include parameters that influence the occurrence of cerebral ischemia (…
To visualize occult endoleaks in patients after endovascular abdominal aortic aneurysm repair.
To establish the relationship between the presence of CYP2C19 loss-of-function alleles in patients receiving clopidogrel after EVAR and the incidence of atherothrombotic events.
The primary objective is to greatly reduce incidence of ischaemic spinal cord injury (SCI, potentially resulting in permanent paraplegia) and mortality - the most devastating complications resulting from open surgical and thoracoabdominal…
Primary objectiveTo establish whether EVAS results in a reduced post-operative inflammatory response , reflected by a lower incidence of the post-implant syndrome, during the first year after surgery, compared to EVAR as assessed by trends in…
This study has two objectives: 1. To compare the mobility of the hypogastic artery during the cardiac cycle before and six weeks after implantation of the Gore IBE device in conjunction with its dedicated self expandable Internal Iliac component (…
The purpose of the study is to determine how a single administration of rifampicin influences the uptake and breakdown of clazosentan. Furthermore, the safety and tolerability of clazosentan when administered after administration of rifampicin, will…
The purpose of the Valiant Evo International Clinical Trial is to demonstrate the safety and effectiveness of the Valiant Evo Thoracic Stent Graft System in subjects with a descending thoracic aortic aneurysm (DTAA) who are candidates for…
To identify which patient characteristics and biomarkers can contribute to a better prediction of complications in patients with thoracic aortic disease. This will result in better risk-prediction with reassurance of low-risk individuals and…
This study investigates the safety and tolerability of deferoxamine use in patients with aneurysma subarachnoid hemorrhage.
The objective of this study is to determine the incidence of chronic Q fever and seronegativity in vascular patients that were seropositive after the Dutch Q fever outbreak. Seropositivity can indicate a past resolved Q fever infection or chronic Q…
The main objective of this study is to find biomarkers for the prognosis of the BAV patients by investigating ECFC and EPC functioning, and to gain knowledge on physiological and pathological processes in patients by investigating molecular…
The primary aim of this study is to evaluate the relation between wall characteristics and recently detected aneurysm growth. The secondary aim is to investigate the relation between intraaneurysmal hemodynamics and wall characteristics.
The objective of this study is to assess performance of navigation in the arterial tree by using catheters and guidewires that are enabled with FORS-based guidance as add-on to X ray imaging, in aortic and peripheral endovascular procedures.
This study aims at investigating potential relevant QT effects of clazosentan at supra therapeutic doses in healthy male and female subjects using a concentration/response analysis approach in compliance with the ICH E14 guidance [FDA 2017].Primary…