469 results
In this investigation we want to regain more insight in the cardiovascular risk profile of RA patients. Also we want to find out which patients should have more attention concerning their cardiovascular risk profile and probably therapy for…
Primary Objective: In this study we investigate the adipose tissue depot-specific differences in adipocyte function and inflammation in patients with T2DM and subjects suffering from CVD compared to healthy subjects.Secondary Objective: Characterize…
To establish the accuracy and precision of systolic cardiac time intervals and arterial pulse wave velocity as obtained from multiple M-mode carotid artery ultrasonography. And to test whether the non-invasive tonometer pressure waveform is…
Primary: To investigate whether high-resolution MRI, 18F-FDG PET, and microemboli detection, or a combination of these techniques, enable to identify patients in the 30-69% stenosis group with an increased stroke risk. Secondary: To compare the…
1. To study the rate of change of diastolic and systolic LV function and LV structure, and the incidence of heart failure over a 7-year period in subjects with and without DM2 2. To study the potential determinants of accelerated deterioration of LV…
To demonstrate the equality of a heparin bonded ePTFE covered stent-graft with the femoropopliteal bypass for long lesions in the superficial femoral artery
This study will evaluate the effect of approximately 10 years of pravastatin treatment on IMT in young adults with FH. Furthermore, safety parameters and psychological aspects with respect to early treatment initiation will be investigated.
To examine whether a self-help psychological intervention program, based on relaxation, changing negative coping styles and finding new goals would be useful for people with PAD.
The primary objective of this study is to evaluate the diagnostic accuracy of coronary artery luminal stenosis and corresponding myocardium perfusion defects in patients with suspected coronary artery disease by use of volume computed tomography..…
Inflammatory and endothelial parametersTo investigate the influence of factor VIII concentrate infusion on inflammatory and endothelial parameters in patients with severe hemophilia A.Platelet activity and responsivenessTo investigate the influence…
Comparison of the VSC clip applier system versus the conventional methods to create an anastomosis or patch angioplasty at the level of the common femoral artery.
In vitro characterization of T lymphocytes from human atherosclerotic lesions.
In this trial, current usual care concerning cardiovascular education is described. Second aim is to study what is understood of this education by the patient. Last aim is to study what effect training of GP's on this subject will have on the…
The objective of the study is to see whether oral administration of probiotics can modulate certain immunological markers which are associated with accelarated atherosclerosis in patients with ANCA associated vasculitis.
To assess whether the non-invasive duplex method can reliably determine diameters and flow characteristics in the LIMA origin of LIMA-LAD versus Y-bypass grafts late after CABG in relation to-the number of distal anastomosis-the adaptation to…
The objective of this study is to to develop a selective and non-selective whole brain ASL perfusion stress test and at 3.0 Tesla based on ASL flow territory measurements.
1) To assess the the natural course of atherosclerotic disease in the carotid artery. 2) to evaluate whether a change in plaque volume, composition and morphology can be predicted based on risk factor profiles, baseline plaque status and shear…
To investigate the relation between premature cardiovascular disease and glycocalyx perturbation
Does flow-mediated dilatation of the brachial artery induce coagulation and inflammation? How long does this possible effect continue? Which parameters are influenced by FMD?
To study the effect of transient high blood glucose level on the brachial artery FMD response, and to determine the reproducibility of the measurements and observed effect.