174 results
In the current study, we want to demonstrate Rienso uptake in the vessel wall in patients with cardiovascular disease and relate the uptake of Rienso to endothelial permeability.
Test the optimized MRI sequences/technology against CTA as gold standard, in terms ofimage quality, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), speed, and accuracy/reproducibility of extracted quantitative parameters.
optimization of a new 3 Tesla Magnetic Resonance Imaging protocol for imaging of the aortic vessel wall in order to enhance the identification of individuals at highest risk of developing clinically manifest atherosclerosis
Primary Objectives:A. To assess the reproducibility and variability (interscan, intra- and interreader) of novel (DCE-)MRI techniques to measure vessel wall dimensions, wall shear stress and vessel wall permeability in healthy and cardiovascular…
To examine the hour-to-hour and day-to-day reproducibility of the CAV-test in young and older humans
The main objective of this study is to assess the prevalence cardiovascular disease and the prevalence of risk factors for cardiovascular disease in patients with gout, and to quantify the risk for cardiovascular disease in patients with gout. The…
The main objective is to show whether imaging characteristics assessed at baseline can predict clinical events in patients with a 30-69 % symptomatic carotid stenosis.
Assess feasibility of development of skin colour independent assessment of skin AGE accumulation by measurement of skin autofluorescence in persons with dark skin
The main goal of this study is to assess the difference in local pulse wave velocity measured at three different points in the left and right carotid artery in healthy subjects and in patients with symptomatic and asymptomatic carotid plaques. As…
* To determine the minimum effective dose of 5-aminolevulinic acid (Gliolan) for adequate MitoPO2 measurements during upper endoscopy.
A study to explore three different diagnostic tools (predictors) (tcPO2 measurement, BOLD MRI and DCE MRI) quantifying the degree of tissue perfusion and oxygenation at the intended amputation level in patients with refractory critical limb ischemia…
Objectives: Part 1) To assess the prevalence of PA in general practice (part 1 of this study);Part 2) To describe differences of cardiorenovascular damage in newly diagnosed hypertensive patients with versus without PA (part 2 of this study);Part 3…
To investigate whether children with a history of Kawasaki disease have an increased IMT and arterial stifness compared to their healthy siblings.
Validation of CT angiography and MRI protocols to identify the different components of the atherosclerotic plaque in the carotid arteries compared to and histology.
The aim of this study is to perform a head-to-head comparison between SPECT/CT and PET/CT in comparison with conventional catheter-based coronary angiography and FFR measurements, to establish the diagnostic value of the modern cardiac myocardial…
Evaluation of I-FABP as diagnostic tool in mesenteric ischemia.
1. Evaluation of differences in free fatty acid (FFA) profiles of several adipose tissue depots, expressed as FFA ratios, between metabolically healthy obese subjects and metabolically unhealthy obese subjects (e.g. subjects with metabolic syndrome…
The main objective of this study is to assess perfusion of the foot and correlate perfusion values with arterial patency. To this end, first the PCT protocol of the foot in patients with CLI needs to be optimized in terms of contrast dose…
The primary objective is to assess the difference in absence of binary restenosis rate of endovascular treatment of intermediate and long lesions of the superficial femoral artery with the Legflow® PEB and nitinol stent, when compared to uncoated…
Primary- MRI: correlation between neovascularisation in carotid atherosclerotic plaque characteristics assessed by dynamic 3.0 Tesla MRI and carotid atherosclerotic plaque at histology. - CT: correlation between size of lipid-rich-necrotic-core in…