174 results
Primary objectiveIs RRSO at age <= 45 in BRCA1/2 mutation carriers a risk factor for development of subclinical atherosclerosis, independent of traditional cardiovascular risk factors? Secondary objectiveAre menopausal symptoms in BRCA1/2…
The main objective of this pilot study is to determine if 31P MRS and BOLD-MRI or 1H MRS can be used as diagnostic tests to discriminate between ischemic muscle and normally oxygenized muscle and to assess their reproducibility.
The objective of this study is to assess the diagnostic performance of Ultra-high field 7 Tesla (T) MRA to detect significant coronary stenoses.
The purpose of this study is to advance our understanding of the behaviour of the coronary microcirculation in the setting of NSTE-ACS, to provide insights into the relationship between Doppler flow velocity and thermodilution-derived coronary…
Comparison of the lipid panel between Afinion POCT en routine chemistry analyzer.
Primary Objective: • To demonstrate that changes in blood pressure and cerebral perfusion (induced with paced breathing and the Cold-pressor test) can be assessed in the MRI using the combination of NIBP and rapid ASL measurements. Secondary…
4.1 The main questionWhat is the effect of temporarily stopping PPI use on the stomach wall uptake of Tc99m Sestamibi with a myocardial perfusion?4.2 Sub-questions:- What is the relative maagwanduptake a myocardial perfusion Tc99m Sestamibi with…
To determine the feasibility of the MitoPO2 measurements during upper endoscopy.
The objective of this study is twofold. First objective is to determine the reproducibility and inter-rater reliability of Perfusion Angiography. The second is to investigate the predictive value of Perfusion Angiography for wound healing in…
Investigate the stability and reproducibility of PAI when applied to the diabetic foot. Further, we aim to compare results from PAI with the currently used non-invasive blood pressure measurements.
To identify local flow patterns that can predict disease progression and failure of stent patency in patients with untreated and treated atherosclerotic lesions in the aortoiliac tract.
The main objective is to assess whether transcatheter arterial embolization of neovessels in patients with symptomatic knee OA results in significant pain reduction after 4 months compared to sham treatment.We hypothesize that novel transcatheter…
Primary Objective: To investigate whether population screening for increased albuminuria among the Dutch population can contribute to the early detection of yet undiagnosed risk factors for renal and cardiovascular diseases in an early stage. For…
To determine the accuracy of computational fluid dynamic models for the quantification of the pressure gradient of tandem stenoses in the femoropopliteal artery, as compared to invasive pressure measurements.
To investigate the development of white matter lesions, changes in cerebral perfusion and cerebral vascular structures on 3T and 7T MRI following carotid revascularization
Primary Objective: The Primary outcome is to evaluate the sensitivity of the ACCmax compared to the currently advised diagnostic method the ABI.Secondary ObjectivesTo evaluate the sensitivity, specificity, positive and negative likelihood ratios of…
This pilot study aims to investigate the feasibility and clinical performance of tissue perfusion measurements with EPOS in the feet/legs in healthy volunteers and patients with PAD. The EPOS system has not yet been CE approved, and has not been…
We aim to validate a panel of plasma biomarkers and investigate volatile biomarkers that potentially allow early and accurate identification of acute intestinal ischemia in patients. Second, we aim to identify a volatile organic compound (VOC)…
This is a pilot study to assess the feasibility and tolerability of mitochondrial oxygenation measurements in patients with moderate to severe claudication (Rutherford class 4-6) with the COMET device in combination with Alacare. As secondary aims…
Primary objective: in this study, we want to investigate the performance of FH identification with a new approach using existing clinical laboratory data in which patients with severe hypercholesterolemia (LDL-C > 99.5th percentile for age…