157 results
The aim of the study is to investigate the effect of statins on ery-apoB levels.
To evaluate anti-inflammatory effects of statin therapy on vessel wall inflammation by means of FDG PET/CT in AS patients.
To investigate the innate pro-inflammatory response in young patients (<50 years of age), who suffer from a myocardial infarction. The pro-inflammatory response will be examined by the search for *trained immunity* especially in the monocytes…
To explore FDG-PET/CT to quantify the effect of CABG on inflammation in the arterial wall.
To investigate the risk of deeath and incident (cardio)vascular disease in patients with a TIA or stroke aged 18-50 yearsTo investigate the riks of cognitive impairment and (vascular) dementia in patients with a TIA or stroke aged 18-50 yearsTo…
The purpose of this study is to make it possible to make a prediction of risk of amputation stump wound healing without the need for re-intervention and whether a secondary amputation.
The primary objectives of our study are:1. to compare the diagnostic performance of coronary CTA with coronary MRA to detect significant coronary stenoses (> 50% reduction in lumen diameter), in patients with a range of coronary calcium…
The aim of this project is to gain insight in which somatic, cognitive and psychosocialfactors contribute to preservation of functioning, in order to identify older people with potentialrisk of functional decline in an early stage and develop…
The overall objective of this project is to assess the interplay between classical risk factors (including lifestyle factors), plasma markers, markers of activated circulating cells and atherosclerosis burden at MR imaging (expressed as aortic…
- To determine the difference in baseline mucosal oxygen saturation measurements and after luminal feeding between patients diagnosed with CGI and healthy subjects. - To determine the difference in baseline mucosal oxygen saturation measurements…
To establish whether there are differences in monocyte function in patients with high expression levels compared to low expression levels of microRNA *x*.
To assess the changes in cardiac function and the microcirculatory function in different thyroid states. We aim to identify how thyroid state affects changes in micro and macro hemodynamics.
In this study we aim to investigate whether infusion of intestinal microbiota from lean (vegetarian) donors has differential effect on choline (d6-labeled choline) and carnitine (d3-labeled carnitine) metabolism and macrovascular inflammation (18F-…
to investigate the risk of death and incident cardiovascular diseaseto investigate the risk of mild cognitive impairment and incident (vascular) dementia
To study the impact on intra-arterial ATP infusion on Annexin A5 targeting.
Determine effect of asprin and simvastatin on platelet and monocyte gene expression in vivo.
To compare the rapidity of onset and the extent of oxidative stress lowering of atorvastatin with that of an (in terms of LDL lowering) equipotent dosage of simvastatin.
To evaluate whether an increase in inflammatory- and coagulation parameters can be found in healthy volunteers with elevated hsCRP levels compared to age and BMI matched healthy volunteers with normal hsCRP levels
We hypothesise that EC dysfunction is present in SLE and WG patients compared to controls. In summary, our hypothesis leads to the following questions:1. Is EC dysfunction, measured by SAE, present in SLE patients?2. Is EC dysfunction related to EC…
In vitro characterization of T lymphocytes from human atherosclerotic lesions.