227 results
To evaluate image quality and accuracy of detection of perfusion defects associated with pulmonary pathology on iodine maps of the lung that are created by two different CT techniques: 1. A standard of care CTPA with DECT and 2. A new technique that…
Objective 1: To prospectively evaluate the utility of C-FLOW monitor to examine status of regional CBF and reperfusion in patients presenting with acute anterior circulation ischemic stroke syndrome. Objective 2: To assess the feasibility,…
Optimization of safety of risk stratification for outpatient treatment in pulmonary embolism, through randomization between Hestia approach with or without NT-proBNP measurement.
Primary objectiveTo assess the outcome of NOAC associated bleeds and emergency invasive surgery or procedures. Secondary objectives1) To describe the treatment of patients presenting with NOAC associated bleeding2) To evaluate the current…
The study has two main objectives. The first objective is to estimate the extra yield in detected cases of AF in patients aged 65 years and over, using case finding. The second is to compare three methods to detect AF.
Frequency of PNH in a selection of patients with DVT. In several publications PNH has been described especially in patients with DVT and younger than 30 years of age and/or with DVT on unusual places.
Primary objective: to determine the incidence and location of thrombi in the umbilical venous catheter route during and after umbilical catheterization and in the same route in infants without umbilical catheters. Secondary objectives:A. to…
Main study objective of this study is:To evaluate whether the 320-detector volumetric CT technology can replace carotid duplex scanning and TEE in the diagnostic workup in TIA/IS patients. Specific aims of this main study objective are:1. To assess…
The main aim is to investigate clinical effects of different implementation methods of online supported self-management for thrombosis patients in primary care. Secondary objectives include well-being, health care use and actual use of the portal.…
The goal is to investigate wether a PNH clone could be the cause of an unexplained thrombosis. In the population of patients with unexplained thrombosis a PNH clone may be the cause.The goal is to investigate whether the prevalence of PNH clones is…
See chapter 'objectives' of study protocol (page 12)
See section 2.2 of the protocol.The main objective of this study is to compare a DAT regimen of 110mg dabigatran etexilate b.i.d. plus clopidogrel or ticagrelor (110mg DE-DAT) and 150mg dabigatran etexilate b.i.d. plus clopidogrel or ticagrelor (…
Main objective:To assess the efficacy of thromboprophylaxis with high prophylactic dose LMWH as compared with standard care without systemic thromboprophylaxis in children treated for primary ALL during asparaginase treatment.Secondary objectives:1…
To determine the within and between variability of pharmacokinetic (PK) profiles in patients treated with DOACs in daily practice
To demonstrate that the use of US-accelerated catheter-derived thrombolysis in patients with recently (less than 7 weeks) thrombosed infra-inguinal bypass grafts or native arteries with half the dose urokinase (50.000 IU/h) will significantly reduce…
Primary Objective: To assess the analytical performance of the cardiac reader Secondary Objective(s): To assess the user friendliness of the device (handling, analytical speed).
The primary objective of this study is to determine the anti-Xa activity after a reduced therapeutic dose of nadroparin in patients with an eGFR < 60 ml/min in comparison with the anti-Xa activity after a standard therapeutic dose of…
In this study, we will assess the reproducibility of the observed dose-dependent inhibiting effect of CK on platelet aggregation.
The primary efficacy objective is to evaluate whether LMWH is superior to VKAs in the long-term treatment of symptomatic VTE in cancer patients who completed 6 to 12 months of anticoagulant treatment. Two aspects are important: the efficacy with…
The purpose of this study is to determine the need for thromboprofylaxis in patients being treated in a below-knee plaster cast after trauma of a lower extremity and if there is, to assess if both of the two tested prophylactic treatments are suited…