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Rosuvastatin use to improve the coagulation profile in patients with venous thrombosis: The STAtins Reduce Thrombophilia (START) Study

To understand why statins are able to decrease the risk of developing venous thrombosis, by analyzing whether statins can influence pathways that inhibit coagulation.

New Oral Anticoagulants (NOAC) Study: Investigation of laboratory tests an development of a gold standard test for monitoring dabigatran and rivaroxaban therapy

Choosing the most suitable laboratory test and setting up a gold standard test to measure dabigatran. Additionally, determining maximal and minimal concentrations of the drug.

Single dose open-label PK/PD, safety and tolerability of dabigatran etexilate mesilate given at the end of standard anticoagulant therapy in successive groups of children aged 2 years to less than 12 years and 1 year to less than 2 years.

To provide single dose PK/PD dataTo investigate tolerability and safety of dabigatran etexilate solution in children1 to <12 years of age

Short and tall body height and the effect on venous blood flow

To investigate the effect of different sitting positions that are experienced in public transport by people of taller or shorter height than average on venous blood flow.

Echocardiographic evaluation of left atrium flow patterns in relation to atrial fibillation and stroke

This study has three objectives:1. To describe flow patterns in the left atrium in patient with sinus rhythm and atrial fibrillation. 2. To prospectively verify the data in patients with atrial fibrillation3. Correlation of abnormal flow patterns to…

Plasma anti Xa-levels in obese patients undergoing bariatric surgery and receiving low molecular weight heparins for thromboprophylaxis.

The purpose of the proposed study is to investigate the anti-Xa levels of enoxaparin in patients after bariatric surgery and to correlate these with actual body weight.

Highlow study: Low-molecular-weight heparin to prevent recurrent VTE in pregnancy: a randomized controlled trial of two doses

To evaluate the efficacy and safety of intermediate dose LMWH versus fixed low dose LMWH in pregnant women with a history of previous VTE.

IntegRAted chronic care program at specialized AF clinic versus usual CarE in patients with Atrial Fibrillation, a Multicenter Randomized Controlled Clinical Trial

Primary Objective: To show that an integrated chronic care program in a specialized AF clinic reduces cardiovascular hospitalizations and mortality.Secondary Objective(s): 1) To demonstrate the benefits of an integrated chronic care program in terms…