14 results
To establish a point prevalence of asymptomatic proximal lower extremity DVT in patients admitted to the ward with COVID-19.
To assess the safety and effect of edoxaban in Chil-Pugh B cirrhosis.
Primary objective: To evaluate anti-Xa trough levels in addition to anti-Xa peak levels in patients with renal insufficiency or obesity. Secondary objectives: To explore relations between patient characteristic such as creatinin clearance,…
The central question of this study is *What is the effect of supplementation of regular therapy with 8 weeks of HR after a first, acute, proximal DVT of the lower extremity on objective aspects of thrombus resolution which are associated with the…
In this study researchers want to learn about the safety of drug Osocimab at low and high doses in adult participants with kidney disease undergoing regular dialysis. Patients with kidney disease undergoing regular dialysis are at high risk for…
The main objective of the study is to explore whether the addition of BAY 2433334 will lead to a dose response in reducing symptomatic strokes and covert brain infarcts and whether this is combined with no relevant increase in bleeding when given on…
To better treat and understand bleeding and thrombotic complications of these diseases and treatments, more insight is needed into the pathophysiology. WIth the findings of the current study we would like to increase knowledge on how platelets (and…
The study will be performed in 2 parts, Part 1 and Part 2. Part 2 has been clinically completed. The remainder of this document concerns Part 1 only. The purpose of Part 1 of this study is to determine the reversal of the blood thinning effects of…
To improve our understanding on the etiology of proximal DVTs, to identify risk factors for stent reinterventions and to optimize treatment after a venous stent. To improve patient education and expectation after a venous stent.
The purpose of this study is to investigate how quickly and to what extent BAY 2433334 is absorbed, broken down, and eliminated from the body (this is called pharmacokinetics). The pharmacokinetics of BAY 2433334 administered as a tablet will be…
The main objective of this study is to detect occurrence of SECI after trans-radial access in interventional radiology procedures. The secondary objective is to determine if there is a difference in the incidence of silent stroke after approach…
1. To investigate the efficacy of dual therapy (omitting acetylsalicylic acid) compared to triple therapy in patients with atrial fibrillation and acute coronary syndrome.2. To investigate the safety of dual therapy (omitting acetylsalicylic acid)…
The primary objective is:i. To determine the safety and tolerability of single or multiple doses SLN360 in subjects with elevated Lp(a) levels. The secondary objectives include assessment of the following:i. PD effects of single and multiple doses…
The primary objective of this study is an analytic validation of D-dimer tests with capillary whole blood of five different, recently introduced POC laboratory devices compared with a central routine lab D-dimer assay. Secondary objective is a…