26 results
Study 1:1) To test the hypothesis that Liraglutide improves cardiovascular function in DM2 patients and whether the improvement is associated with redistribution of ectopic fat stores. 2) To test the hypothesis that Liraglutide activates BAT in DM2…
To prevent vessel damage of the radial artery by using the Cordis Railway sheathless guiding catheter system.
The objective of the study is to obtain information on the bioavailability and pharmacokinetics of the phenolics present in an olive leaf extract (Bonolive®, dose 250 mg), standardized on 40% oleuropein, and to identify the composition of the…
1) to investigate cognitive functioning in lacunar infarct patients with and without periventricular white matter lesions; 2) to identify predictors for cognitive dysfunction in lacunar infarct patients.
The aim of this study is to elucidate the effects of RT on the oral microcirculation in patients with malignant disease in the head and neck region. We want to test the hypothesis that radiation therapy triggers microcirculatory derangements which…
The goal of this research project is to find out to what extent people with aphasia suffer from reduced processing capacity. We will use new insights from healthy language processing providing quantitative measures of "complexity" to…
The objective of the study is to assess the impact of the physical form of five different cocoa matrices on the bioavailability of the monomeric flavan-3-ols. Assessment and evaluation will be done by comparing the kinetics of the main study…
To assess structural changes in the radial artery wall 3 hours and 30 days after catheterization with a 6 F sheath for diagnostic or interventional coronary procedures and elucidate arterial healing patterns that might explain early radial artery…
To further investigate the application in a clinical setting we aim to set up a model in which we can investigate the protective effects in an in vitro model, where subjects blood serum is used to transfer the protective effect of RIPC onto cells…
The aim of this study is to investigate the effect of a MSE intervention on social participation and quality of life in chronic stroke patients. This MSE intervention will be compared to a controlgroup in order to measure the additional effect of…
The overall aim of the proposed research project is to investigate systematically the therapeutic potential of mental practice embedded in daily therapy on the improvement of daily activities of adult stroke patients compared to therapy as usual…
To evaluate the long-term clinical effectiveness of patients with IC randomized for supervised exercise training orendovascular revascularization.
The objectives are to explore in a step-wise approach the possibility to study reactive hyperemia and ischemia-reperfusion phenomena in humans by simultaneous assessment of vaso-reactivity and autonomous nervous system function.
The overall aim of the proposed research project is to investigate the therapeutic potential of mental practice embedded in daily therapy on the improvement in daily activities of adult patients with Parkinson*s disease and stroke patients. In the…
Determine if there is a difference in permeability of the blood brain barrier between the twodifferent types of cerebral small vessel disease.
to investigate the safety and efficacy of idarucizumab in reversing the anticoagulation effect of dabigatran, in patients who have uncontrolled bleeding or require emergency surgery or invasive procedures.
See section 2.2. of the protocol.The primary objective of this trial is to assess the safety of an uninterrupted dabigatran etexilate periprocedural anticoagulant regimen compared to an uninterrupted warfarin regimen in NVAF patients undergoing AF…
the primary aim is to determine the effect of thawed deep-frozen platelets re-suspended in thawed deep-frozen plasma versus room temperature stored platelets in platelet additive solution for transfusion on the percentage of patients with surgical…
Primary objective: to study whether pyridoxamine supplementation in type 2 diabetes improves microvascular function in the eye, kidney and skin, and reduces markers of endothelial dysfunction and glycation.Secondary objective: to study whether…
To investigate whether the collagen-based MANTA vascular closure device (VCD) is superior to suture-based VCDs in preventing vascular access site complications in patients undergoing transfemoral transcatheter aortic valve replacement.