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Sleeve Gastrectomy and the Influence of Concomitant Hiatal Hernia Repair

To define the exact effect of LSG with and without concomitant HH repair on the prevalence of GERD and GERD-related symptoms in obese patients who are intraoperatively diagnosed with a small HH. Furthermore, to examine the effect of LSG on the…

Consequences of liver surgery for liver function and cell injury

1 Primary Objective To investigate the effects of 15* liver ischemia versus 30* liver ischemia on liver injury and liver function.To investigate the effect of liver manipulation during mobilisation for a right hemihepatectomy, that can be used as a…

Effect of mechanical ventilation on plasma cytokine concentrations in healthy humans

Our primary goal is to compare the effects of a positive pressure mechanical ventilation with spontaneous breathing on systemic cytokine release in patients with normal pulmonary function. Secondly, the possible effects of surgery on the ventilation…

Chronic post-sternotomy pain, relation between accompanying painsymptoms and painlocation on the sternum

The objective of this study is to prove that chronic post-sternotomy pain is not a local painproblem, but part of a general painsyndrom.Our hypothesis is twofold:1. The investigated painsymptoms are of more frequently occurrence in the pain-sample…

Perioperative changes in the microvascular perfused boundary region in patients undergoing coronary artery bypass grafting

To identify the influence of two different biocompatible-coated extracorporeal circuits on the perfused boundary region of the sublingual microvasculature as measured by the GlycoCheck Sidestream Darkfield Imaging camera.

Teres Major versus Latissimus Dorsi tendon transfer in posterosuperior RC tears: a randomised controlled trial

The study is primarily designed to compare the clinical outcome between the TM transfer and the LD transfer in patients with a massive posterosuperior rotator cuff tear. Our secondary objective is to asses the quality of life in patients undergoing…

Brachiocephalic arteriovenous fistulae: two different techniques of bloodless surgery and their effect on fistula stenosis.

The primary aim of this study was to compare bloodless surgery using vascular clamps and a tourniquet with respect to the development of an anatomical or hemodynamic significant stenosis in patients with a brachiocephalic or radiocephalic AVF.

Treatment considerations for the surgical therapy of peri-implantitis

The primary objective of this study is to examine clinical and radiographical parameters when executing:- adjuvant antibiotic therapy versus no antibiotic therapy in the resective surgical treatment of 0-, 1- and 2-wall bone defects due to peri-…

Optimising surgical anastomosis in ileocolic resection for Crohn's disease to reduce recurrent disease: A Randomized controlled trial comparing hand-sewn (END-TO-END or Kono-S) to stapled anastomosis (END2END study)

To understand if handsewn (end to end and Kono S side to side) anastomoses is superior to side to side stapled anastomosis after ileocolic resection for Crohn's disease with respect to endoscopic recurrence, gastrointestinal function and costs.