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Platelet function in minimal extracorporeal circulation versus conventional extracorporeal circulation in coronary artery bypass grafting

This study evaluates if there is a difference in platelet function during and following the use of minimal ECC compared with conventional ECC in coronary artery bypass grafting (CABG) analysed with tromboelastography en multiple electrode aggrometry…

Peripheral Vascular Disease and Health status

Primary research question:To evaluate the impact of open versus endovascular invasive treatment in different types of surgery (AAA, CEA, LLR) on health status. Secondary research questions:To examine the prognostic impact of quality of life in PAD…

The influence of hemodialysis and vascular access surgery on systemic circulation and microcirculation: a validation study

Primary objective* To investigate the correlation between cutaneous microcirculation (using LSCI), finger and toe pressures and shunt flow in hemodialysis patients.Secondary objectives* To investigate the variability in basal flow measured with LSCI…

A pilot study on the cause of recurring cerebral thrombo-embolic events after Branched Thoracic Endovascular Aneurysm Repair

This is a pilot study for investigating the cause of recurring cerebral thrombo-embolic events in a patient after (branched) TEVAR surgery. The main aim of this logistical pilot is to develop a workflow for investigating blood flow patterns in such…

Mast cell activation in stable versus unstable human atherosclerotic plaques

The main objective is to investigate whether local mast cell activation correlates with an unstable phenotype of the atherosclerotic plaque.Secondary objectives are: 1. To investigate whether elevated systemic mast cell markers are correlated to…