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Smartphone virtual reality exposure before paediatric surgery: effects on pre- and post-procedural pain and anxiety

The objectives of this study are to (1) test the efficacy of sVRE versus CAU in 180 children undergoing surgery on the postoperative pain of the child (primary outcome), postoperative analgesics use, anxiety level of the child during induction of…

Effect of cryo- and compression therapy after Total Knee and Unicompartmental Arthroplasty, A Randomised Controlled Trial*

Primary objective:Investigating the effect of the use of cryo- and compression therapy during the first 6 postoperative weeks after surgery (TKA en UKA) on the perceived pain in rest at 6 weeks postoperative.Secundary objectives:Investigating the…

Determining the causative agent and optimal duration of antibiotic therapy in persons with diabetes and foot osteomyelitis: BonE BiOPsy (BeBoP) trial

Primary Objective: To prospectively compare outcomes of subjects with diabetic foot osteomyelitis treated with antibiotics targeted at culture results from bone biopsy (intervention group) versus therapy targeted at ulcer bed biopsy culture results…

Surgical use of 3D printed cages as adittion for the filling of large bone defects, a randomised controlled trial

To investigate whether the addition of a custom made 3D printed scaffold to standard treatment increases healing and decreases the need for secondary surgery in segmental defects of long bones with a length of more than 5 cm compared to the standard…

Migration in Total Hip Arthroplasty with a Cemented BiMobile cup: Better stability with more cement?

The main objective of this study is to compare the (early) migration of the cemented BiMobile cup at two year post-surgery between 2 different cup sizes after standard optimal reaming, and therefore adjusting the amount of cement into 2 or 4…

FeelGood: Increasing perioperative positive emotions by Cognitive Bias Modification

To study the efficacy of preoperative CBM in patients with increased anxiety levels undergoing knee- or spine surgery with expected postoperative moderate to severe pain.

Effectiveness of dual-mobility cups for preventing dislocation after primary total hip arthroplasty by a posterolateral approach and their cost-effectiveness compared to unipolar cups in elderly patients.

The primary objective is to investigate whether there is a difference in the number of hip dislocations and revisions following primary total hip arthroplasty (THA), using the posterolateral approach, with a DM cup compared to a unipolar cup in…

Non- or minimally displaced distal radius fractures in adult patients <50 years of age: Three weeks of cast immobilisation versus one week of brace immobilisation, a Multicenter Randomised Controlled Trial.

Current literature indicates that one week of cast or brace immobilisation is safe, however, no level one evidence is available. This trial aims to compare one week of brace immobilisation with three weeks of cast immobilisation in non- or minimally…

HIPPI shoulder - Hip-allograft In Proximal humerus fractures versus Plate Implantation alone: a randomized controlled trial

The aim of this RCT is to examine the differences in functional, clinical, and radiological out-comes, between LCP fixation alone and femoral allograft augmentation in addition to LCP. Ultimately, the purpose is to optimize treatment strategies and…

ARP versus SH

To assess and compare ARP to spontaneous healing in damaged sockets (&gt;50% buccal bone loss) in the posterior mandible regarding the additional need for bone augmentation either prior to or during implant placement 4-6 months after tooth…