43 results
4.1 Primary• To estimate the Sensitivity and False Positive rate of OTL38 for malignancy detection during Near Infrared Imaging (NIR).• To assess the safety and tolerability of single intravenous doses of OTL384.2 Secondary• To assess the safety of…
In our current study we would like to evaluate a newly developed surgical platform for minimal invasive cardiothoracic surgery: the soft tissue expander. Main objective of the study is to determine the feasibility of creating a trans tissue expander…
(1) Investigate diagnostic performance (sensitivity) of HD bronchoscopy, with or without surface enhancement or tone enhancement in comparison to standard WLB for detecting abnormalities of the tracheobronchial tree. Furthermore we aim to…
To determine whether SRT achieves a local control rate comparable to surgery in patients with metastatic lung disease.
Determine arm and shoulder function and quality of life scores before and after treatment of SST. The untreated extremity can serve as a control.Determine riskfactors for a poor functionale outcome and quality of life after treatment for SST (e.g.…
The aim of the study is to compare the ease of placement, the incidence of malpositioning and the quality of lung deflation of a left DLT and a EZB. Secondly, the incidence and severity of damage to laryngeal, tracheal and bronchial structures…
Primary: Assessment of the short-term effect of a Heat and Moisture Exchanger on tracheal mucociliary clearance in laryngectomized individuals. Secondary: The relationship between clinical assessment, ciliary activity and mucociliary clearance.
To study the effect (signal, accuracy) of varying CO2 blood gas levels as well as different capillary blood temperatures on the SpO2 sensor signal. From the data obtained in this study the feasibility to derive the arterial CO2 value at 0.3 kPa…
To study the macro- and microcirculatory effects of VV-ECMO treatment.
The aim of this study is to compare nasal and oral insertion and to determine which of them is more comfortable and less time consuming for the patient.
The primary objective is to assess whether a 10-14 day Merocel with TC packing of the sinus is better than a one day Merocel with TC packing in the improvement of clinical and sinus parameters in patients with symmetrical CRSwNP following FESS. The…
To compare the outcomes of stereotactic radiotherapy (experimental arm) with that following primary surgery (standard arm) in a prospective phase III trial.
To establish platelet function and primary hemostasis during lung transplantation
Determining the effectiveness of commonly used premedicating agents in reducing subclinical stress responses in newborns during intubation.
Het bestuderen en vergelijken van cocaïne, tetracaïne-oxymetazoline en ropivacaïne-oxymetazoline wat betreft de peroperatieve decongestie en hemostasis en postoperatieve analgesie die zij bieden bij FESS. Study and compare the peroperative…
Primary objective:Determing the positive predictive value and diagnostic yield of HD+ i-scan bronchoscopy for vascular pattern detection .Secondary objectives:1. To investigate the correlation of vascular abnormalities with histology2. To…
To study the effect of surgery and SABR on both immunostimulatory (with primary endpoint CD8 positive cells)and immunosuppressive cells in peripheral blood in patients with early stage non-small cell lung cancer who are treated with either modality.
In our current study we would like to evaluate a newly developed surgical platform for minimal invasive cardiothoracic surgery: the soft tissue expander. Main objective of the study is to determine the feasibility of creating a trans tissue expander…
In The Netherlands 2% of women and 4% of men suffer from Obstructive Sleep Apnea Syndrome (OSAS). NCPAP, the gold standard therapy for moderate to severe OSAS has been shown to reduce blood pressure in OSAS. NCPAP therapy is however hampered by…
To examine the predictive value of daily physical activity (steps/day) (DPA) of lung cancer surgical patients, measured by a pedometer, on postoperative morbidity.To examine the relationship between the daily physical activity (pedometer-assessed…