371 results
Primary objective: To evaluate the expected increase of the Microvascular Flow Index perioperative using a SDF-imaging device and the systemic inflammatory response by measuring inflammation biomarkers.Secondary objective: To learn more about the…
To directly evaluate the gastric tube microcirculation with Dark Sidestream imaging during minimal invasive esophageal resection on several locations, i.e. from best arterial blood supply (antrum) to worst (fundus). Furthermore, to evaluate the…
Primary objective is to evaluate the use of deep muscle relaxation versus on indication only on surgical and anesthesia conditions in patients for endoscopic esophageal resection.Secondary objective is to evaluate the (hypothetical) dose of…
Determining the surplus value of telehealth in addition to the standard program after a bariatric procedure
Since imatinib easily and rapidly dissolves at pH 5.5 or less, a lack of gastric acid secretion might be causing the decreased exposure in the patients that underwent major gastrectomy. Therefore we would like to study if the exposure to imatinib in…
Primary Objectives:This study consist of:1) a prospective cohort study in which all patients with esophageal cancer, selected for esophagectomy, and willing to be included in this cohort, are followed to assess their complications, short en long…
The primary objective of this study is to compare a semi-mechanical with a hand sewn cervical anastomosis after esophagectomy with gastric tube reconstruction for cancer.
This is a feasibility study of the System to assess safety and performance in patients scheduled to undergo esophagectomy.
In this study the effect of the pneumoperitoneum on the intestine of children is objectified by measuring the iFABP levels in the urine, as an indicator for the ischemia or damage to the intestine. To exclude any iFABP increase due to intestinal…
The above mentioned literature shows that repair of a hiatal hernia using a mesh gives fewer recurrences than repair without mesh. However, there are few prospective randomized controlled trials that provide clear results about this. The most…
Decrease of carotid intima media thickness after bariatric surgery as marker of reduction of cardiovasculair disease.
This study is performed in order to study the population pharmacokinetics and pharmacodynamics of propofol and nadroparin in morbidly obese patients with a total body weight higher than 170 kg. The recently developed and published pharmacokinetic…
To identify predictive variables correlated with percentage excess weight loss, reversal of metabolic complications of obesity and quality of life and postoperative complications; to identify metabolic variables correlated with markers of the…
In the Netherlands, gum chewing has not been incorporated in the standard postoperative care after intra-abdominal surgery. Therefore a multi-center RCT was set up to evaluate the influence of gum chewing on the development of ileus. Our null…
The goal of this study is to investigate the feasibility of distant, internet-based follow-up and monitoring of the weigth of 20 gastric bypass patients. Our research results will determine whether or not the use of the Youw8 weight scale is…
Uptill now, no randomised controlled trial , comparing the saftey and per and postoperative complications for cholecystectomy in patients with symptomatic uncomplicated cholecystolithiasis, for this 3 different procedures of cholecystectomy, is…
The primary objective of this study is to investigate target site penetration of cefazolin in morbidly obese patients. Also, we aim to investigate whether cefazolin plasma concentrations are predictive of subcutaneous (target) cefazolin…
The aim of this study is to evaluate the effect of supplementation of a high oral dose of omega-3 fatty acids on hepatic steatosis and glucose metabolism in morbidly obese patients undergoing laparoscopic Roux-Y gastric bypass surgery (LRYGBP).
In this pilot study experience will be obtained in diagnosing POCD and its risk factors, in elderly surgical cancer patients.
Objective: To compare patient outcome following standard of care (laparoscopic right hemicolectomy) and an alternative, established, recognized therapy (SILS right hemicolectomy) for the treatment of right colonic tumors.