371 results
Determine the feasibility of a study on the effectiveness of an integrated physiotherapy strategy aimed at promoting healthy physical activity during and after hospitalization. If the pilot project proves to be feasible, a multicenter randomized…
This study will be performed to evaluate the effectiveness of the EndoBarrier device for the treatment of obesity 3 years after surgery.
The aim of this monocenter observational pilot study is to determine the incidence and severity of gastric emptying disorders in patients with a hiatal hernia and to observe the effects of hiatal hernia repair and fundoplication on the gastric…
To define the exact effect of LSG with and without concomitant HH repair on the prevalence of GERD and GERD-related symptoms in obese patients who are intraoperatively diagnosed with a small HH. Furthermore, to examine the effect of LSG on the…
Our primary aim is to tackle the factors of frailty in an early phase, which is possible in elective planned surgery. We hypothesise that optimal preparation, starting 5 weeks before surgery, will reduce the incidence of delirium from 15 % to 7.5…
In the current study, we intend to study the diagnostic accuracy of promising urine biomarkers for early detection of acute kidney injury in patients undergoing major general surgery. The study is designed to validate earlier findings in a large…
To assess the feasibility of nano-MRI in the evaluation of locoregional lymph nodes metastases in patients with esophageal cancer whom underwent nCRT and to study the effect of nCRT on the detection of locoregional lymph nodes metastases with nano-…
Primary Objective: To investigate the feasibility of a 12 -week postoperative Telerehabilitation program for patients with esophageal cancer treated with esophagectomy and suffering from postoperative complicationsSecondary Objective: To investigate…
The objective of this study is to evaluate the ability to reduce the number of OR personnel required while performing the following procedures: colon resections (right hemicolectomy, left hemicolectomy/sigmoid resection), anti-reflux/hiatal hernia…
Primary objective:- to study the safety, tolerability and feasibility of gastrectomy combined with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) after neoadjuvant systemic chemotherapy as primary treatment option for…
Achieving an improvement on quality of life and a positive effect on pain, nausea, fatigue, sleeping disorders, mood and experience of stress by offering complementairy care.
This study has a strong explorative and qualitative approach and set-up. Please note that the goal of the study is to further identify possible areas for innovation for professionals, patients and their partners. The aim for this study is NOT to…
Validate the presence and correlation of intraoperative modifiable risk factors for colorectal seam leaks.
The overall aim of this observational prospective study is to evaluate the association between a) the trajectory of cerebral oxygenation, activity and perfusion as evaluated by NIRS, aEEG, Zonare Doppler Ultrasound and Cytocam-IDF during and 24…
Main objective of this project is to establish the maximum tolerable dose (MTD) and recommended phase II dose of intraperitoneal irinotecan in patients with PC of colorectal origin, added to standard of care systemic chemotherapy. Other endpoints…
The aim of this trial is to investigate which treatment option is superior in the treatment of anemia in patients undergoing surgery in terms of hemoglobin increase, postoperative morbidity, amount of bloodtransfusions needed, length of stay,…
The aim of this present feasibility study is to determine the safety and preliminary accuracy by which we can intra-operatively detect residual disease in esophageal tumor and lymph nodes. This study is set up as a prospective multi-centre dose…
The aim of this study is to investigate the effect of two distalisation techniques of a gastric bypass in revisional surgery with standardised limb lengths in total weight loss (TWL) and the need for treatment for protein calorie malnutrition (PCM…
The primary objective of this pilot trial is to evaluate if adding mitoPO2 monitoring to standard anaesthetic management enables tissue oxygenation optimisation.
Primary objective: 1. To develop and evaluate a model for prediction of deterioration necessitating escalation of care, based on continuous vital signs recordings, self-reported patient symptoms, nurse observations, clinical measurements, and…