113 results
primary objective:-to define the optimal glucose intake by quantifying endogenous glucose production and fractional gluconeogenesis in critically ill children.secundary objectives:-determine glucose utilization in relation with exogenous glucose…
Optical Tissue Stylet - descriptive observational study into paravertebral space detection in humans
The primary objective of the trial is to investigate if the optical tissue stylet technology can reliably identify the thoracic paravertebral space. Diffuse reflectance spectra will be acquired during needle advancement, with custom-made needle…
The first aim is to test the effect of the surgical intervention for fear of blushing in a randomized controlled trail consisting of a robot-assisted highly selective dorsal sympathectomy and a waiting list control group. There are several outcome…
The effect of the intervention on pain an regain of function in de affected extremity. This will be quantified in multiple questionnaires at baseline and three follow-up points, and by clinical evaulation of the hand function at baseline and two…
This study is dedicated to obtain accurate broadband (400 - 1830nm) diffuse reflectance spectra of human nerve tissue in vivo (which knowledge creates possibilities to design useful imaging devices).
The primary objective is to avoid cognitive and affective side effects and maintain the beneficial motor effects by selective stimulation of the STN motor part. With the Select Stim project we want to improve the classical operation procedure, in…
The primary endpoint of this feasibility study is the technical success of positioning the SLIDE device to verify the speed and ease of use without unexpected device related adverse events. A technical success is defined that the SLIDE device was…
Does anesthesia itself or transition of anesthesia to an awake state and vice versa lead to changes in the lactate/pyruvate ratio, glucose, glycerol and glutamate concentration as measured in the brain interstitial fluid?Are the metabolic…
To examine the effect of surgical trauma on mucosal perfusion, intestinal epithelial damage, the inflammatory response and potentially sepsis, following surgery remote to the abdomen in adults, children and neonates,
To determine if dose-intensifying the adjuvant temozolomide component of the chemoradiation treatment enhances treatment efficacy as measured by overall survival.
The main goal of this study is to map the functional anatomy of the anterior optic radiations by correlating the visual field defects to the surgical defects in Meyer*s loop in epilepsy patients after temporal lobectomy.
The primary objective of this study is to characterize functional brain networks in patients considered for (i) epilepsy surgery and (ii) tumour surgery with epilepsy surgery techniques. Characterization will be done preoperatively (MEG), during…
To accumulate data from patients who undergo spinal surgery for metastatic cancer, for the purposes of determining the difference in outcome between operations of varying complexity.
The primary goal of this study to investigate the long term functional and radiological outcome of those patients that underwent a cervical laminectomy in the treatment of a cervical spondylotic myelopathy.The secondary goal is to determine those…
To assess whether there is less peri-operative pain and a faster post operative recovery.
Safety and performance will be based on a comparison of overall success rates of the Barricaid ARDand either a concurrent group (nonrandomized) of control patients treated by conventional surgicalmethods (e.g., noninstrumented discectomy) at select…
1. Investigate whether per-operative subcortico-muscular (LFP-EMG) coherence can be used as a predictor for favourable surgical outcome in DYS and PD tremor patients undergoing DBS surgery 2. Investigate whether pre-surgical EEG-EMG-coherence and…
Primary objective:1. To assess functional outcome of patients with an osteoporotic vertebral compression fractures after one year of follow-up.Secondary objectives:1. To assess radiological deterioration of sagittal alignment during one year of…
1. To implant a functional vestibular prosthesis using the ampullar *V*-approach, as developed in our own clinic.2. To investigate protocols for adjusting the vestibular implant (VI) to required settings, regarding:-- Modulation sensitivity--…
Our objective is to obtain insight into whether and how the visual and auditory systems of hemispherectomized patients have adapted after brain damage and brain surgery in early life. For this purpose we will perform psychophysical tests and (…