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individueel setpoint Hypothalamus Hypofyse Gonade as bij de man; een pilotstudy

To study whether there is an individual setpoint for the hypothalamus-pituitary-gonad axis in men

Reproductive function, ovarian reserve and risk of premature menopause in Dutch female childhood cancer survivors

The overall aim of this study is to examine, in adult female CCS in the Netherlands, the effects of treatment in general, and the effects of different types of treatment, doses of drugs, radiation sites and doses, and age at time of treatment, on: 1…

The prevalence of Premature Ovarian Failure (POF) and Fragile X-associated Tremor Ataxia Syndrome (FXTAS) in families with FMR2 gene mutation (FRAXE).

More knowledge about the clinical aspects of the FMR2 gene mutation can complete the couseling. Carriers with the desire to start a family can take the chance on POF in consideration. The clinical symptoms of FXTAS can be differentiated from other…

Anti-oxidative function and composition of high-density-lipoprotein (HDL) in the polycystic ovary syndrome

Primary research questionDo obese PCOS women with reduced insulin sensitivity have HDL particles that have impaired anti-oxidative function in comparison with lean controls with normal insulin sensitivity?Secondary research questionDo obese PCOS…

LH and FSH relaese by the pituitary, de inhibitive effect of estradiol in male to female transsexuals

to study the effect of estradiolapplication on gonadotropin relaese in young and older men in the abscense of circulating testosterone.