17 results
Imaging disease activity in patients with Graves' orbitopathy using [18F]-FDG-PET/CT - a pilot study
To determine whether 18FGD-PET/CT imaging is able to show difference in [18F]-FDG uptake in orbital tissue between patients with active and inactive GO.
The study aims to determine the value of combined 124I PET and FDG PET to avoid futile treatment with 131I. Secundary aims are to validate functional imaging with histopathological correlation, and to optimize and standardize the new 124I technique…
To find out if the mean thyroid volumes of healthy 10-12 and 17-18 years old Dutch children and adolescents are the same or larger than in the late nineteen nineties, and if the dietary iodine intake of these children and adolescents has decreased…
ObjectiveThe main goal of this investigation is to evaluate the thyroid hormone response in patients with TMNG and control subjects in response to various pharmacological and physiological stimuli, administered according to the dynamic exposure test…
Main objectiveTo describe the experienced pain sensations of temperature and to describe the different temperature sensitivity thresholds using Quantitative Sensory Test (QST) in the different patient groups.secondairy objectiveAs a measure of the…
The aim of our study is to investigate whether PTH levels measured between 4-24 hours after surgery can accurately identify patients with permanent hypoparathyroidism after thyroid surgery who need long-term calcium supplementation.
- Objective (Study) 1.To evaluate the clinical performance of MET PET during rhTSH stimulation and to compare the results of this MET PET with the clinical rhTSH stimulated FDG PET in patients with negative post-treatment 131I-whole body scan (WBS)…
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To evaluate the occurrence of thyroid dysfunction children and young adults with NB and other childhood malignancies , who received diagnostics with 123I-MIBG
Primary Objectives- To determine the optimal dose of the VEGF-A targeting NIRF tracer bevacizumab-IRDye800CW for an adequate tumor-to-background ratio (TBR) in PTC/FTC/HTC/PDTC lymph node metastases.Secondary Objectives- To evaluate the feasibility…
Primary objective: To assess and compare the difference in thyroid gland secretion capacity by measuring maximal FT4 and FT3 response upon intramuscular administration of 0.9mg Thyrogen assessed by AUC0-48hours in SCT subjects and healthy controls.…
The main objective of the research is to differentiate between benign and malignant thyroid nodules using the GC-IMS for the analysis of breath, urine and blood in a (multicenter) study and reduce the amount of unnecessary surgery.
The aim of this study is to identify whether we can improve laboratory diagnostics in patients with hypothyroidism receiving thyroid hormone supplementation. We will investigate whether, in addition to the current laboratory tests of TSH and fT4,…
Therefore, this feasibility study will evaluate whether the 18F-PSMA PET/CT is capable of MTC lesion detection. Moreover, we will compare its ability to detect MTC lesions with a routinely used PET scan, the 18F-FDG PET. By exploring new tracers in…
2.1 Primary Objective- To determine the optimal dose of the c-Met targeting NIRF tracer EMI-137 for an adequate tumor-to-background ratio (TBR) in PTC lymph node metastases.2.2 Secondary Objectives- To obtain information on safety aspects of…
Primary objective: - obtain an comparison in diagnostic results of two methods of ultrasound assisted fine needle aspiration biopsies (FNAB) of the thyroidal gland in the Jeroen Bosch hospital (JBZ).Secondary objective:- can the cytological thyroid…
The main goal of this pilot study is to investigate the feasibility of the identification of the parathyroid glands by means of the present commercially available near infrared fluorescence imaging system during thyroid surgery: is it possible to…