14 results
The primary objective of this study is to demonstrate that free field word recognition scores in quiet and noise with CI *ON* are significantly better than the best aided pre-implant scores in the ear to be implanted (contralateral ear plugged)…
The objective of the study is to answer the following questions:a) Does the PLS-strategy improve pitch- and speech-perception?b) How does the number of harmonics in consecutive channels influence frequency discrimination, in speech coding strategies…
To investigate which surgical technique (with or without vein graft interposition) is most (cost-)effective in patients with otosclerosis in terms of the average postoperative air-bone gap (ABG) closure, individual air and bone conduction thresholds…
Hypothesis: PLS will improve speech understanding in noise in comparison to HiRes, an exisiting state-of-the-art speech coding strategy. The objective is to test this hypothesis. A secondary hypothesis is that PLS improves pitch perception. A…
To objectify the effect of the VLS-system during daily use regarding postural stability and quality of life.
The basic safety of the surgical procedure and the DACS actuator as well as the basic efficacy of the DACS were already shown in the DACS Chronic Clinical Trial (see protocol). The safety of the C-DACS ID receiver/stimulator, which replaces the…
Primary objective The primary objective of the study is the evaluation of the therapeutic benefit of three repeated dose intratympanic AM 101 injections in comparison to placebo in the treatment of persistent acute inner ear tinnitus following acute…
The ENT clinic in Groningen has developed a new speech coding strategy: phase-lock speech (PLS) coding. This strategy distinguishes from existing strategies by the explicit coding of acoustic fine-structure. In normal hearing subjects, the…
Primary objective: to investigate the prevalence of vestibulotoxicity and disturbance of equilibrium as far a Cystic Fibrosis patients with at least one treatment with tobramycin are concerned. Secondary objective: To formulate an advice for…
To assess the effect of betahistine on the severity / intensity of motion sickness
To determine if maintenance therapy with AZN will provide significant improvements in PCD lung disease, compared to placebo: reduction in respiratory system exacerbations and improvement in lung function, ventilation inhomogeneity, improvement in…
To establish the clinical and cost-effectiveness of antibiotic-corticosteroid eardrops as compared with oral antibiotics in children with AOMd.
This study has been transitioned to CTIS with ID 2024-512860-75-00 check the CTIS register for the current data. The aim of this feasibility study is to validate pre-treatment [89Zr]-bevacizumab PET/CT as an imaging biomarker for prediction of…
This study has been transitioned to CTIS with ID 2024-513658-31-00 check the CTIS register for the current data. The primary objective of this study is to assess the efficacy of a single intratympanic injection of AC102 compared to oral steroids in…