103 results
Although this procedure has been performed for more than 20 years and clinical results after myectomy combined with AMVLE are satisfactory, very little is known about the effect of surgical myectomy intervention on the blood flow through the aortic…
The purpose of this study is to evaluate the safety and effectiveness of the Aveir wireless dual-chamber pacemaker system in the treatment of patients with slow or irregular heartbeats.
To identify host risk factors through genetic and immunological screening that may be associated with the development of cardiac SAEs following CHMI. Identification of such factors may on the one hand allow at-risk individuals to be screened out…
Primary Objective: 1. To investigate the effect of CRT on markers of pancreatic exocrine functioningSecondary Objectives: 1. To compare changes in markers of pancreatic exocrine function between CRT responders and non-responders2. To compare the…
Number of patients with >=80% reduction of VT burden, i.e., any ICD-treated or highly-symptomatic VT episodes, at one year after STAR compared to the year before (including VTs during the 8 week-blanking period). Efficacy parameters will be…
To establish the safety and effectiveness of the Edwards SAPIEN 3/ SAPIEN 3 Ultra Transcatheter Heart Valve (THV) in subjects with moderate, calcific aortic stenosis (AS)
The overall aim of this pilot is to evaluate the technical feasibility and clinical implementation of the Stroke Box by evaluating user experience and hypertension management. The primary objective is gathering data on blood pressure management for…
Monitor ongoing safety and performance of the CORCYM heart valve devices and accessories for aortic, mitral and tricuspid valvular diseases in a real-world setting.
Compare Atellica VTLi reference plasma separation membrane with at least one alternative plasma separation membrane using hs-cTnI values from capillary whole blood from fingerstick, Li-Hep whole blood and plasma from venipuncture.
The primary objective of the trial is:To assess whether a non-surgical, fractional flow reserve (FFR) and optical coherence tomography (OCT)-guided treatment strategy* has a comparable outcome (MACE) with surgical revascularization of significant…
To investigate the effect of short term TRE on the innate immune system in patients with a history of myocardial infarction.
Primary objective: to study in patients with heart failure and AF whether PVI or atrioventricular node ablation is non inferior with regard to all-cause mortality, cardiovascular hospitalization or changes in quality of life. Secondary objective: to…
This study aims to evaluate the effect of AZD4831 on functional improvement and reduction of symptoms in participants with heart failure with left ventricular ejection fraction > 40%. Additionally, the PK and overall safety profile of AZD4831…
Primary: to investigate the effectiveness of using Hospital Fit as part of the physiotherapy treatment on average time spent walking per day in patients hospitalised at the Medical Oncology or Cardiology Departments of the Maastricht University…
The goal of this study is to determine if MDMA use is associated with a relevant risk of toxic valvulopathy. The popularity of the drug is attributed to its assumed low-risk profile, but these assumptions could be incorrect due to underreporting of…
to quantify atrial electropathology of the endocardium in adult patients with CHD and to correlate clinical characteristics, atrial volume, electropathology, atrial ectopy and features of pre- and post-procedural atrial fibrillation.
The main aim of the LOFIT study is to determine the (cost) effectiveness of a hospital-based dedicated LFO in comparison with usual care 12 months after participation
Primary objective: Our primary objective is to investigate whether niagen normalizes blood-based energy metabolites, mitochondrial levels and proteostasis levels. Secondary objective: To examine whether niagen reduces AF burden in patients with…
Main research question: Does (handgrip) exercise provoke vasoconstrictive responses of the coronary arteries in patients with suspected ANOCA with clinically indicated coronary function test including acetylcholine provocation test?Secondary…
Primary aim: To establish reference values for exercise-induced elevations of cTn concentrations following walking, cycling and running exercise. Secondary aim: Assess the prevalence of (sub)clinical coronary artery disease in individuals with high…