53 results
The main objective of this study is to obtain more insight in the (human) mechanism underlying BVR by assessing the correlation between response of BVR to preload variation in study subjects (with and) without electrical remodelling (based on…
The main objective of this study is to assess whether ICD therapy in dialysis patients reduces sudden (arrhythmogenic) cardiac death. The first secondary end point is to compare total mortality death between the two groups. An other is to evaluate…
Primary Objective: 1. To investigate the anatomical location of a TAVI-induced LBBB. Secondary Objectives: 1. To investigate during which phase of the TAVI-procedure the conduction disorder develops.2. To investigate predictors for the occurrence of…
Area of interest (study setting): Specific aims:Transient triggers and chronic riskfactors (case-crossover and casecontrol)(1) To investigate frequency and strength of association between transient physical andpsychological triggers and early-onset…
Primary objective: to identify intra-individual changes of clinical and biochemical markers of AT characteristics before, and one year after bariatric surgery by:* Determining circulating AT derived biomarkers * Determining local AT biomarkers in…
To investigate the real incidence of POAF a Reveal device is implanted. Afterwards a risk stratification of POAF is made.Using modern mapping equipment and techniques, it is now possible to investigate the substrate for development of atrial…
1) To improve our understanding of the underlying pro-arrhythmic substrate and electrophysiologic mechanisms of VA in NICM, and to develop individualized treatment for VA based on the identified substrate. 2) To improve risk stratification for VA…
The main objective is to find markers for arrhythmia vulnerability in patients with end stage heart failure.
Primary objective:To assess the two-year prevalence and incidence of clinical relevant arrhythmias in drug-resistant epilepsy.Secondary objective:To assess whether the recorded cardiac arrhythmias are related to epileptic seizures (subjectively from…
1) To evaluate the feasibility and the acute effect of intra-operative cryoablation of the slow conducting anatomical isthmuses (endpoint bidirectional conduction block) and on the re-inducibility of monomorphic isthmus dependent VT. 2) To study the…
- To determine the effects of the pacing site on prevention of AF episodes - To examine the relation between the pacing site, reduction of AF episodes, quality of life, heart failure, number of cardioversions, frequency and duration of hospital…
To establish evidence on the effectiveness of long term rhythm observation using an implantable loop recorder for detecting atrial fibrillation in patients with cryptogenic stroke.
Primary Objectives: 1. To assess the values of ARI and APDR in NICM patients. 2. To assess the three-dimensional heterogeneity of ARI and APDR in NICM patients.3. To compare 1. and 2. with the same data collected from non-NICM patients.4. To…
To phenotype and genotype the population of patients with IVF in our cohort, and to find alternative diagnoses as a cause of the event of VF.
The aim of this project is to elucidate how corticosteroids protect cardiac surgical patients from PNAF. We will therefore examine the modulating effect of prophylactic high-dose corticosteroid administration on perioperative risk factors for PNAF.…
The objective of this study is to investigate cardiac sympathetic ativity in subjects with 22q11DS and the effect of catecholamine depletion.
1. To compare the induction of a procoagulant state between patients undergoing PVI using the PVAC catheter, the cryoballoon catheter or the cooled tip catheter.2. To compare the incidence of CE on diffusion weighted MRI between the three groups of…
The objective of this study is to determine the frequency of previously undiagnosed SCN5A mutations leading to sudden death in temporal association with vaccination in The Netherlands.
1) To electrophysiologially characterise a selected, large cohort of patients prone to malignant ventricular arrhythmias (ICD recipients)2) To exactly quantitate outcome by total mortality as well as malignant arrhythmia risk through number of…
This study that documents the changes in heart rate, muscle sympathetic nerve activity, stroke volume and systemic vascular resistance in response to supine and head up tilted carotid sinus massage in elderly subjects.