386 results
- Enrolment of a representative cross-section of AF patients in Europe.- Detailed analysis of clinical and relevant parameters (digitalised ECG, cardiac imaging, blood biomarkers) that could be used during clinical practise for the diagnosis of…
This IDE trial is proposed herein to gather clinical data on the safety and effectiveness of a hybridsinus node sparing ablation procedure utilizing the AtriCure ISOLATOR Synergy Surgical AblationSystem to obtain an IST indication.
The primary objective of this study is to determine if left atrial appendage closure with the WATCHMAN FLX device is a reasonablealternative to non-vitamin K oral anticoagulants (NOACs) in patients with non-valvular atrial fibrillation.
Primary objectives: The first aim is to examine the role of microtubule network in electrical conduction, protein localization and function in induced cardiomyocytes from pediatric BrS patients, life threatening ventricular arrhythmia patients and…
The main aim of this study is to improve knowledge on the hemodynamic burden of labour in women with cardiac disease and women without cardiac disease, by examining CO trajectory through the full course of labour. Therefore, we specified the…
The objective of this trial is to evaluate the safety and effectiveness of the Amulet device compared to NOAC therapy in patients with non-valvular AF at increased risk for ischemic stroke and who are recommended for long-term NOAC therapy.
The primary objective of this acute feasibility study is to assess the defibrillation threshold (DFT) when adding a second left parasternal electrode to an S-ICD system.The secondary objective is to assess the efficacy of the 2-electrode…
1. Assess the spatial resolution of pace-mapping using the PaSoTM software to identify the site of origin of outflow tract idiopathic PVCs2. Compare the spatial resolution of pace-mapping using the PaSoTM software for PVCs originating from the RVOT…
This study has been transitioned to CTIS with ID 2024-511190-30-00 check the CTIS register for the current data. To investigate the feasibility of a definitive RCT to assess the efficacy and safety of verapamil and quinidine in patients with short-…
The main objective of this study is to gain insight in the (reverse) remodeling process of the atria in patients with atrial fibrillation. T Analyses will be conducted on the cardiac tissue and blood samples. We aim to correlate the findings from…
The primary objective is to study whether AF ablation, as opposed to pharmacological rhythm management (rate and/or rhythm control according to ESC guidelines), can reduce the incidence of the composite primary endpoint of CV death and CV…
The main objective is to study whether flashforward (FF) EMDR alone is effective in reducing anxiety symptoms in ICD patients.
The Check@Home consortium aims to set up a roadmap and infrastructure for a (cost-)effective program to early detect atrial fibrillation and chronic kidney disease (defined by elevated albuminuria) in the general population. Furthermore, the project…
The objective of the VOLT-AF study is to demonstrate that the Volt* PFA System (Volt PFA System) is safe and effective for the treatment of symptomatic, recurrent, drug refractory paroxysmal and persistent atrial fibrillation (AF).
In this study, we aim to compare two different techniques for the second ablation in patients who have previously undergone an unsuccessful ablation. The first technique is called "radiofrequency ablation," and the second technique is…
Demonstrate that a risk score, based on non invasive long term ECG, can predict the absence of arrhythmias requiring ICD intervention or the absence of sudden death, with a >90% certainty (NPV) in patients with a reduced LVEF currently…
The purpose of this study is to confirm the safety and defibrillation efficacy of the Next Generation ICD Lead when placed in the Left Bundle Branch Area Pacing (LBBAP) location in an Implantable Cardioverter Defibrillator (ICD) or Left Bundle…
Collect clinical data in order to confirm the clinical safety and performance of the Pamira lead when used in routine clinical practice to support the regulatory post-market strategy in Europe and other regions and validation of promotional claims…
Primary objective: To compare the number of episodes of atrial fibrillation detected by the Corsano CardioWatch 287-2 during 28 days of use with the number of episodes of atrial fibrillation detected by conventional Holter monitoring during 48 hours…
Primary Objective: 1. To evaluate the ablation lesion characteristics of different ablation modalities and strategies Secondary Objectives: 2. To evaluate the ablation lesion characteristics of different ablation energy profiles; 3. To evaluate the…