11 results
Primary and Secondary: To assess cardiovascular function and the presence and magnitude of myocardial injury using echocardiography and cardiac magnetic resonance (CMR) imaging, among community-dwelling individuals who recovered from Covid-19…
The primary objective is to study the association between baseline (including genetic), and repeatedly measured blood biomarkers (including metabolomics and proteomics), and the incidence of cardiovascular disease. Secondary objectives are related…
The primary objective is to investigate whether treatment with JAK inhibitors improves cardiac function, reduces myocardial inflammation and favourably alters coronary plaque morphology in patients with rheumatoid arthritis. The secondary objective…
This study has been transitioned to CTIS with ID 2023-505438-85-00 check the CTIS register for the current data. The primary objective of the study is to assess the clinical efficacy of selatogrel when self-administered upon occurrence of…
The main objective of this event-driven trial is to demonstrate the superiority of empagliflozin 10 mg once daily versus placebo, in addition to standard of care, for the reduction of the composite endpoint of time to first heart failure…
Demonstrate that primary Left Ventricular unloading and a thirty-minute delay-to-reperfusion, when compared to the control cohort, treated according to the current standard of care treatment of Anterior STEMI, has the following effects:1. Reduction…
By performing this study, in case the results are positive (SMS images are equally diagnostic as compared to current imaging techniques), the SMS sequence can be implemented in standard clinical care for patients referred for cardiac MRI, reducing…
The aim of this adaptive multicentre randomized controlled trial is to maintain patients at a target blood pressure level with a sufficient margin from the minimal acceptable blood pressure threshold of a MAP of 65 mmHg to reduce the incidence of…
This study has been transitioned to CTIS with ID 2024-513310-36-01 check the CTIS register for the current data. Primairy objectives 1. To determine the presence and extent of myocardial microcalcification and myocardial denervation in ATTR-CM;2. To…
The aim of this registry is to compare functional status among patients with highly symptomatic obstructive HCM despite optimal medical treatment who undergo Alcohol Septal Ablation to Surgical Septal Myectomy. This study will therefore, compare the…
The ultimate goal of the consortium is to use state-of-the-art imaging, genetics, and machine-learning techniques to identify NCCM patients at risk for severe arrhythmia or stroke and guide preventive therapy using personalized risk scores