140 results
To investigate the acceptability and feasibility of exercise therapy in an aquatic environment by patients after burn injury.
Primary Objective: Pilot study to identify the optimal patch test concentration for detecting contact allergy to ME-PPD in subjects with a proven contact allergy to PPD, who may be allergic to ME-PPD. Hypothesis: In this study subjects will be…
Primary:To determine the prevalence of pruritis in patients with hidradenitis suppurativa.Secondary:- to evaluate pruritis severity and its effect on three elements of daily activities;- to evaluate differences in extensiveness of HS in relation to…
Collect data to determine whether early pimple markers can be identified using images and a skin expert review or algorithm for at least 1 day before they are visible (visible or tangible) for the subject (self-detection).
The main objective of this study is to investigate the effect of a topically applied emollient enriched with barrier lipids on the barrier properties of skin of AE patients.
The aim of the project is to study the effect of COM test compounds on typical skin features of psoriasis. This information can establish the most effective compound, right formulation and dose for further clinical research.
To determine the prevalence of pruritus and pemphigoid in nursing home patients.To assess the relationship of demographic and medical risk factors with pemphigoid in nursing home patients.To assess the association between pruritus and…
With this pilot feasibility study, the feasibility of and satisfaction with an eHealth and serious gaming training based on psychological expectancy mechanisms are evaluated.
The aim of the project is to study the effect of SNA on the gene expression in psoriasis lesions. This information can establish the right formulation and dose of SNA for further research.
The aim of the project is to study the effect of chromene derivatives on gene expression in psoriasis lesions. This information can establish the right dose of chromene derivatives for further research.
To obtain a comprehensive overview of long-term (*5 years after burn injury) consequences after burn injuries, both in all patients admitted to burn centre admissions and in a subgroup of patients who suffered from more extensive burns.
The main objective is to evaluate the cytokine response to histamine iontophoresis in vivo, dynamically and non-invasively by means of transdermal analysis patches. The secondary objective is to correlate the cytokine response with morphological…
The aim of the project is to study the effect of GRT on the synthesis and cytokine release in psoriasis lesions. This information can establish the right formulation and dose of GRT for further research.
Primary objective* To characterize and monitor wound healing after a standardized, induced skin trauma Secondary objectives* To evaluate safety and tolerability of biopsy-induced skin trauma
ln this study effect of 3 novel compounds on the development of psoriasis in the humanized mouse model isinvestigated. The efficacy is compared to one registered drug, namely Remicade(R).
Characterization and extending the use of the humanized mouse model for psoriasis for pre-clinical testing of new drug.Limited screening of compound B for a pharmaceutical company.Therefore, depending on the success rate of transplantation and…
To gain insight in the effects and cost-effectiveness of the introduction of laser Doppler imaging in burn care.
In previous projects a number of compounds were tested that had a positive effect in the transplant model of psoriasis. However, it proved difficult to prepare formulations that were stable enough to use in clinical studies. A new compound (CD07813…
ln this study the effect of 2 novel compounds on the development of psoriasis in the humanized mouse model is investigated. The efficacy is compared to one registered drug, namely Stelera.
The objective of this study is to find out the relevance of adding isobornyl acrylate to the (meth) acrylate. Sub question: What is the relevant test concentration of isobornyl acrylate?